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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Alterations in acetyl coenzyme A carboxylase activities in voles and mice treated with monosodium aspartate.

Changes of body weights and hepatic acetyl-CoA carboxylase activities were measured in voles and mice treated with monosodium-L-aspartate (MSA). MSA was administrated subcutaneously to neonates at 4 mg/g. The MSA-treated mice showed remarkable obesity, associated with the increase in the plasma insulin concentrations and acetyl-CoA carboxylase activities. The activity of acetyl-CoA carboxylase of control voles was very low; under half that of mice. In the MSA-treated voles, although the plasma insulin concentrations also increased, acetyl-CoA carboxylase activities were not elevated and signs of obesity were not observed.[1]

References

  1. Alterations in acetyl coenzyme A carboxylase activities in voles and mice treated with monosodium aspartate. Arai, T., Sasaki, M., Shiomi, M., Nonaka, T., Ochiai, K., Oki, Y. J. Vet. Med. Sci. (1992) [Pubmed]
 
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