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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Acute vestibular neuritis visualized by 3-T magnetic resonance imaging with high-dose gadolinium.

Sudden idiopathic unilateral loss of vestibular function without other signs or symptoms is called acute vestibular neuritis. It has been suggested that reactivation of human herpes simplex virus 1 could cause vestibular neuritis, Bell palsy, and sudden unilateral hearing loss. Enhancement of the facial nerve on gadolinium-enhanced magnetic resonance imaging (MRI) is a common finding in Bell palsy, but enhancement of the vestibular nerve has never been reported in acute vestibular neuritis. We present 2 consecutive cases of acute vestibular neuritis where high-field-strength MRI (3.0 T) with high-dose (0.3 mmol/kg of body weight) gadolinium-pentetic acid showed isolated enhancement of the vestibular nerve on the affected side only. These findings support the hypothesis of a viral and inflammatory cause of acute vestibular neuritis and might have implications for its treatment.[1]


  1. Acute vestibular neuritis visualized by 3-T magnetic resonance imaging with high-dose gadolinium. Karlberg, M., Annertz, M., Magnusson, M. Arch. Otolaryngol. Head Neck Surg. (2004) [Pubmed]
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