- Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes. Baldus, C.D., Liyanarachchi, S., Mrózek, K., Auer, H., Tanner, S.M., Guimond, M., Ruppert, A.S., Mohamed, N., Davuluri, R.V., Caligiuri, M.A., Bloomfield, C.D., de la Chapelle, A. Proc. Natl. Acad. Sci. U.S.A. (2004)