- Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. Wei, L., Taffet, G.E., Khoury, D.S., Bo, J., Li, Y., Yatani, A., Delaughter, M.C., Klevitsky, R., Hewett, T.E., Robbins, J., Michael, L.H., Schneider, M.D., Entman, M.L., Schwartz, R.J. FASEB J. (2004)