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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Major tumor regression after paclitaxel and carboplatin polychemotherapy in a patient with advanced penile cancer.

Penile cancer is rare in Western countries. High-risk patients are considered for prophylactic inguinal lymphadenectomy. For advanced disease, a triplet drug regimen consisting of bleomycin, methotrexate, and cisplatin is the most active combination tested so far. A 62-year-old man with penile cancer underwent partial penile amputation but presented 10 months later with inguinal nodal metastasis. He received three cycles of paclitaxel/carboplatin with marked clinical and radiologic (computed tomography and positron emission tomography) tumor regression. Later, complete resection of the inguinal nodal metastasis was performed. The paclitaxel/carboplatin combination has potential activity in penile cancer. Positron emission tomography may be used for screening of nodal metastases.[1]

References

  1. Major tumor regression after paclitaxel and carboplatin polychemotherapy in a patient with advanced penile cancer. Joerger, M., Warzinek, T., Klaeser, B., Kluckert, J.T., Schmid, H.P., Gillessen, S. Urology (2004) [Pubmed]
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