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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

In vitro laser ablation of natural marine biofilms.

We studied the efficiency of pulsed low-power laser irradiation of 532 nm from an Nd:YAG (neodymium-doped yttrium-aluminum-garnet) laser to remove marine biofilm developed on titanium and glass coupons. Natural biofilms with thicknesses of 79.4 +/- 27.8 microm (titanium) and 107.4 +/- 28.5 microm (glass) were completely disrupted by 30 s of laser irradiation (fluence, 0.1 J/cm2). Laser irradiation significantly reduced the number of diatoms and bacteria in the biofilm (paired t test; P < 0.05). The removal was better on titanium than on glass coupons.[1]


  1. In vitro laser ablation of natural marine biofilms. Nandakumar, K., Obika, H., Utsumi, A., Ooie, T., Yano, T. Appl. Environ. Microbiol. (2004) [Pubmed]
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