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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Synthesis, characterization and immobilization of Prussian blue nanoparticles. A potential tool for biosensing devices.

Prussian blue (PB) particles with the size of ca. 5 nm were synthesized and immobilized in a multilayer structure, as a strategy for the potential development of an amperometric transducer for oxidase-enzyme-based biosensors. Multilayer films composed of PB and poly(allylamine hydrochloride) (PAH) were prepared via layer-by-layer (LbL) sequential deposition. The process was carefully monitored by UV-vis spectroscopy and cyclic voltammetry. The increase of the redox current peaks during the layer-by-layer deposition demonstrated that charge propagation within the film occurs. Linear increase of UV-vis absorbance with the number of deposited bilayers indicates that well-organized systems have been elaborated. ITO electrodes coated with PB/PAH films were used successfully for detecting H2O2, sensitivity being dependent on the number of PB/PAH layers.[1]

References

  1. Synthesis, characterization and immobilization of Prussian blue nanoparticles. A potential tool for biosensing devices. Fiorito, P.A., Gonçales, V.R., Ponzio, E.A., de Torresi, S.I. Chem. Commun. (Camb.) (2005) [Pubmed]
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