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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Infrared laser light reduces loading time of dental implants: a Raman spectroscopic study.

OBJECTIVE: The aim of this study was to assess, through near-infrared Raman spectroscopy (NIRS), the incorporation of hydroxyapatite of calcium (CHA; approximately 960 cm(1))--on the healing bone around dental implants submitted or not to low-level laser therapy (LLLT) (lambda830 nm). BACKGROUND DATA: The process of maturation of the bone is important for the success of dental implants, as it improves the fixation of the implant to the bone, allowing the wearing of a prosthesis. LLLT has been suggested as a mean of improving bone healing because of its biomodulatory capabilities. METHODS: Fourteen rabbits received a titanium implant on the tibia; eight of them were irradiated with lambda830-nm laser (seven sessions at 48-h intervals, 21.5 J/cm(2) per session, 10 mW, phi approximately 0.0028 cm(2), 85 J/cm(2) treatment dose), and six acted as control. The animals were sacrificed at 15, 30, and 45 days after surgery. Specimens were routinely prepared for Raman spectroscopy. Twelve readings were taken on the bone around the implant. RESULTS: The results showed significant differences in the concentration of CHA on irradiated and control specimens at both 30 and 45 days after surgery (p < 0.001). Conclusion: It is concluded that LLLT does improve bone healing, and this can be safely assessed by Raman spectroscopy.[1]


  1. Infrared laser light reduces loading time of dental implants: a Raman spectroscopic study. Lopes, C.B., Pinheiro, A.L., Sathaiah, S., Duarte, J., Cristinamartins, M. Photomedicine and laser surgery. (2005) [Pubmed]
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