- Pyruvate decarboxylase encoded by the PDC1 gene contributes, at least partially, to the decarboxylation of alpha-ketoisocaproate for isoamyl alcohol formation in Saccharomyces cerevisiae. Yoshimoto, H., Fukushige, T., Yonezawa, T., Sakai, Y., Okawa, K., Iwamatsu, A., Sone, H., Tamai, Y. J. Biosci. Bioeng. (2001)