- Heterologous expression of Vitreoscilla hemoglobin (VHb) and cultivation conditions affect the alkaloid profile of Hyoscyamus muticus hairy roots. Wilhelmson, A., Häkkinen, S.T., Kallio, P.T., Oksman-Caldentey, K.M., Nuutila, A.M. Biotechnol. Prog. (2006)