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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Do gastrointestinal transit times and colonic dimensions change with time since spinal cord injury?

STUDY DESIGN: Long-term follow-up study. OBJECTIVES: To determine whether gastrointestinal transit times (GITTs) and colonic dimensions change during the first or subsequent decades after spinal cord injury (SCI). SETTING: Aarhus University Hospital, Denmark. METHODS: GITT and colonic dimensions were evaluated by means of radio-opaque markers. Group A (n=12) was investigated 1 year after SCI and again 13 (range 11-14) years later. Group B (n=10) was studied 19 (range 9-36) years after injury and again 12 (range 11-12) years later. All had been treated with conservative bowel management. RESULTS: In group A, the median GITT 1 year after injury was 4.3 (range 1.1-6.5) days and 13 years later, it was 3.2 (range 1.3-6.5) days, P=0.96. In group B, the median GITT 19 year after injury was 3.4 (range 0.6-5.9) days and 12 years later, it was 3.2 (range 1.9-5.5) days, P=0.77. None of the two groups experienced a significant change in the diameter of the caecum/ascending colon, transverse colon, descending colon or the sigmoid during long-term follow-up. Megacolon was present in four patients at baseline and in five at follow-up. CONCLUSION: GITTs and colonic dimensions did not change, neither during the first decade nor long after SCI.[1]

References

  1. Do gastrointestinal transit times and colonic dimensions change with time since spinal cord injury? Faaborg, P.M., Christensen, P., Rosenkilde, M., Laurberg, S., Krogh, K. Spinal. Cord (2011) [Pubmed]
 
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