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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Expression of phosphoglycerate mutase mRNA in differentiating rat satellite cell cultures.

Poly(A)+ mRNA was isolated from rat satellite cell cultures and analyzed by Northern blot analyses for mRNA content of phosphoglycerate mutase (PGAM) isozymes. In non-differentiating satellite cells only PGAM-B mRNA was detected, but when cells were differentiated into myotubes, which undergo spontaneous contraction, mRNA for PGAM-M muscle-specific isozyme was also detected. This finding is in perfect concordance with the transition of PGAM isozymes encountered in the same cell cultures, and strongly supports a transcriptional control of PGAM expression throughout myogenesis independently of nerve influence.[1]

References

  1. Expression of phosphoglycerate mutase mRNA in differentiating rat satellite cell cultures. Castellà-Escolà, J., Ureña, J., Alterio, J., Carreras, J., Martelly, I., Climent, F. FEBS Lett. (1990) [Pubmed]
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