The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Alternative activity of beta-lactam antibiotics against methicillin- and cephem-resistant Staphylococcus aureus in the presence of respiratory tract mucus.

Methicillin- and cephem-resistant Staphylococcus aureus (MRSA) strains were found to be unable to grow in sputum from patients treated with a beta-lactam antibiotic. Sputum containing no beta-lactams also exhibited bactericidal activity when the MRSA strain was pretreated with a subinhibitory concentration of a beta-lactam; however, lysozyme-free sputum was inactive. Peptidoglycan of MRSA grown in the presence of cefazolin was susceptible to lysis by respiratory mucus. Hen albumen lysozyme contained the same activity against beta-lactam-treated MRSA. The median minimum inhibitory concentration of cefazolin for 45 S. aureus strains (including 20 MRSA strains) shifted from approximately 50 micrograms/ml to approximately 0.78 microgram/ml by addition of 1 mg/ml of hen albumen lysozyme to susceptibility-testing media. Such lysozyme-dependent antistaphylococcal activity was manifested specifically with beta-lactams (9 penicillins, 10 cephalosporins, 3 cephamycins, 1 oxacephem, and 1 carbapenem).[1]


WikiGenes - Universities