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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

CT and MR imaging of intralabyrinthine schwannoma: report of two cases and review of the literature.

Two cases of intralabyrinthine schwannoma were studied with computed tomography (CT) and magnetic resonance (MR) imaging. On CT scans, a soft-tissue mass was identified in the round window niche in both cases. Widening of the basilar turn of the cochlea and characteristic erosion of the promontory were noticed in one case. Preoperative MR imaging (performed in only one case) revealed a soft-tissue mass in the labyrnth, extending into the round window niche. Findings at CT and MR imaging are discussed, and a differential diagnosis is given. The literature is reviewed. The authors' findings suggest that CT and MR imaging may prove very valuable in the previously difficult preoperative diagnosis of these tumors. In the setting of progressive sensorineural hearing loss, atypical Meniere disease, or recurrent vertigo, the presence of a mass in the labyrinth or labyrinthine windows- delineated on CT or MR images, despite a normal internal auditory canal, cerebellopontine angle, or brain stem - is highly suggestive of intralabyrinthine schwannoma.[1]


  1. CT and MR imaging of intralabyrinthine schwannoma: report of two cases and review of the literature. Mafee, M.F., Lachenauer, C.S., Kumar, A., Arnold, P.M., Buckingham, R.A., Valvassori, G.E. Radiology. (1990) [Pubmed]
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