The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effect of recipient-donor trephine size disparity on refractive error in keratoconus.

A retrospective study was performed to evaluate the effect of recipient-donor trephine disparity on refractive error and corneal curvature post-suture removal in keratoconus. A double running suture technique was used and donor corneas were trephined from the endothelial side. When keratoconus patients with 0.25-mm larger donor than recipient trephines were compared with keratoconus patients with the same size recipient and donor trephines, a statistically significant increase in the mean keratometer value (45.4 and 43.8 diopters [D], respectively; P = 0.03) and increase in myopic spherical equivalent (-3.5 and -1.8 D, respectively; P = 0.03) was found. When keratoconus patients were compared with phakic Fuchs' dystrophy patients (both groups had 0.25-mm oversize donor trephines), the keratoconus group had a statistically significantly higher myopic spherical equivalent (-3.5 and -1.4 D, respectively; P = 0.03) despite only a 0.7-D difference in mean keratometer value which was not statistically significant (45.4 and 44.7 D, respectively). This study supports the hypothesis that the degree of post-penetrating keratoplasty myopia in patients with keratoconus can be decreased by reducing recipient-donor trephine disparity.[1]


WikiGenes - Universities