The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Retrospective Studies

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Retrospective Studies


Psychiatry related information on Retrospective Studies


High impact information on Retrospective Studies

  • From this retrospective study of cryptococcal infections in patients with AIDS we conclude that the addition of flucytosine to amphotericin neither enhances survival nor prevents relapse, but long-term suppressive therapy appears to benefit these patients [11].
  • To assess the risk of these complications we conducted a retrospective study based on 17 autopsied cases of alpha 1-antitrypsin deficiency identified during the period 1963 to 1982 in the city of Malmö, Sweden [12].
  • CONTEXT: Plasma levels of the inflammatory biomarker C-reactive protein (CRP) predict cardiovascular risk, and retrospective studies suggest that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may lower CRP in a manner largely independent of low-density lipoprotein cholesterol (LDL-C) [13].
  • In two retrospective studies, CX3CR1 has been implicated in the pathogenesis of atherosclerotic cardiovascular disease (CVD) based on statistical association of a common receptor variant named CX3CR1-M280 with lower prevalence of atherosclerosis, coronary endothelial dysfunction, and acute coronary syndromes [14].
  • We evaluated this recommendation in a retrospective study of National Surgical Adjuvant Breast and Bowel Project Protocol B-15, in which patients received a combination of doxorubicin and cyclophosphamide (AC), CMF, or AC followed by CMF [15].

Chemical compound and disease context of Retrospective Studies


Biological context of Retrospective Studies


Anatomical context of Retrospective Studies


Associations of Retrospective Studies with chemical compounds

  • An additional retrospective study on the relation between heparin treatment and ICH in SVT patients was based on 102 patients, 43 of whom had an ICH [31].
  • METHODS: This was a retrospective study of the etiologic factors and the clinical course of all acetaminophen-related admissions [32].
  • To obtain data on these issues, we did a retrospective study in which we analysed the concentrations of acylcarnitines in stored neonatal blood spots, and reviewed patients with high octanoylcarnitine concentrations at age 7-9 years [33].
  • In a retrospective study of 280 sera from patients presenting with cerebellar signs, seven of whom had proved positive for the typical paraneoplastic serum antibodies that were requested by the clinicians, raised concentrations of antibodies to voltage-gated calcium channels or to glutamic acid decarboxylase were detected in a further seven sera [34].
  • Retrospective studies indicated that prophylactic antibiotic therapy, particularly with trimethoprim-sulfamethoxazole, significantly prolonged disease-free intervals to greater than 40 months (p less than 0.05) [35].

Gene context of Retrospective Studies


Analytical, diagnostic and therapeutic context of Retrospective Studies


  1. P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. Chan, H.S., Haddad, G., Thorner, P.S., DeBoer, G., Lin, Y.P., Ondrusek, N., Yeger, H., Ling, V. N. Engl. J. Med. (1991) [Pubmed]
  2. Resistance to erythromycin in group A streptococci. Seppälä, H., Nissinen, A., Järvinen, H., Huovinen, S., Henriksson, T., Herva, E., Holm, S.E., Jahkola, M., Katila, M.L., Klaukka, T. N. Engl. J. Med. (1992) [Pubmed]
  3. Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. Halverson, P.B., Kozin, F., Bernhard, G.C., Goldman, A.L. JAMA (1978) [Pubmed]
  4. P-glycoprotein expression: critical determinant in the response to osteosarcoma chemotherapy. Chan, H.S., Grogan, T.M., Haddad, G., DeBoer, G., Ling, V. J. Natl. Cancer Inst. (1997) [Pubmed]
  5. Scl-86, a marker antigen for diffuse scleroderma. van Venrooij, W.J., Stapel, S.O., Houben, H., Habets, W.J., Kallenberg, C.G., Penner, E., van de Putte, L.B. J. Clin. Invest. (1985) [Pubmed]
  6. Neuronal membrane cholesterol loss enhances amyloid peptide generation. Abad-Rodriguez, J., Ledesma, M.D., Craessaerts, K., Perga, S., Medina, M., Delacourte, A., Dingwall, C., De Strooper, B., Dotti, C.G. J. Cell Biol. (2004) [Pubmed]
  7. Creutzfeldt-Jakob disease in France: I. Retrospective study of the Paris area during the ten-year period 1968-1977. Brown, P., Cathala, F. Ann. Neurol. (1979) [Pubmed]
  8. Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression. Pfennig, A., Kunzel, H.E., Kern, N., Ising, M., Majer, M., Fuchs, B., Ernst, G., Holsboer, F., Binder, E.B. Biol. Psychiatry (2005) [Pubmed]
  9. Alcohol and cannabis use in schizophrenia: effects of clozapine vs. risperidone. Green, A.I., Burgess, E.S., Dawson, R., Zimmet, S.V., Strous, R.D. Schizophr. Res. (2003) [Pubmed]
  10. Diltiazem as augmentation therapy in patients with treatment-resistant bipolar disorder: a retrospective study. Silverstone, P.H., Birkett, L. Journal of psychiatry & neuroscience : JPN. (2000) [Pubmed]
  11. Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome. Chuck, S.L., Sande, M.A. N. Engl. J. Med. (1989) [Pubmed]
  12. Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency. Eriksson, S., Carlson, J., Velez, R. N. Engl. J. Med. (1986) [Pubmed]
  13. Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. Albert, M.A., Danielson, E., Rifai, N., Ridker, P.M. JAMA (2001) [Pubmed]
  14. Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans. McDermott, D.H., Fong, A.M., Yang, Q., Sechler, J.M., Cupples, L.A., Merrell, M.N., Wilson, P.W., D'Agostino, R.B., O'Donnell, C.J., Patel, D.D., Murphy, P.M. J. Clin. Invest. (2003) [Pubmed]
  15. HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-15. Paik, S., Bryant, J., Tan-Chiu, E., Yothers, G., Park, C., Wickerham, D.L., Wolmark, N. J. Natl. Cancer Inst. (2000) [Pubmed]
  16. Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia. Matherly, L.H., Taub, J.W., Ravindranath, Y., Proefke, S.A., Wong, S.C., Gimotty, P., Buck, S., Wright, J.E., Rosowsky, A. Blood (1995) [Pubmed]
  17. Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients. The Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Ljungman, P., Deliliers, G.L., Platzbecker, U., Matthes-Martin, S., Bacigalupo, A., Einsele, H., Ullmann, J., Musso, M., Trenschel, R., Ribaud, P., Bornhäuser, M., Cesaro, S., Crooks, B., Dekker, A., Gratecos, N., Klingebiel, T., Tagliaferri, E., Ullmann, A.J., Wacker, P., Cordonnier, C. Blood (2001) [Pubmed]
  18. In situ detection of hepatitis B, C, and G virus nucleic acids in human hepatocellular carcinoma tissues from different geographic regions. Abe, K., Edamoto, Y., Park, Y.N., Nomura, A.M., Taltavull, T.C., Tani, M., Thung, S.N. Hepatology (1998) [Pubmed]
  19. High-grade endometrial carcinoma in tamoxifen-treated breast cancer patients. Magriples, U., Naftolin, F., Schwartz, P.E., Carcangiu, M.L. J. Clin. Oncol. (1993) [Pubmed]
  20. dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer. Ladner, R.D., Lynch, F.J., Groshen, S., Xiong, Y.P., Sherrod, A., Caradonna, S.J., Stoehlmacher, J., Lenz, H.J. Cancer Res. (2000) [Pubmed]
  21. Genetic staging of unresectable or metastatic neuroblastoma in infants: a Pediatric Oncology Group study. Bowman, L.C., Castleberry, R.P., Cantor, A., Joshi, V., Cohn, S.L., Smith, E.I., Yu, A., Brodeur, G.M., Hayes, F.A., Look, A.T. J. Natl. Cancer Inst. (1997) [Pubmed]
  22. Maternal serum alpha-fetoprotein--a marker of fetal aplastic crisis during intrauterine human parvovirus infection. Carrington, D., Gilmore, D.H., Whittle, M.J., Aitken, D., Gibson, A.A., Patrick, W.J., Brown, T., Caul, E.O., Field, A.M., Clewley, J.P. Lancet (1987) [Pubmed]
  23. Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C. Chu, C.J., Hussain, M., Lok, A.S. Gastroenterology (2002) [Pubmed]
  24. Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: a North Central Cancer Treatment Group Study. Garrity, M.M., Burgart, L.J., Mahoney, M.R., Windschitl, H.E., Salim, M., Wiesenfeld, M., Krook, J.E., Michalak, J.C., Goldberg, R.M., O'Connell, M.J., Furth, A.F., Sargent, D.J., Murphy, L.M., Hill, E., Riehle, D.L., Meyers, C.H., Witzig, T.E. J. Clin. Oncol. (2004) [Pubmed]
  25. Alcoholism in hereditary hemochromatosis revisited: prevalence and clinical consequences among homozygous siblings. Adams, P.C., Agnew, S. Hepatology (1996) [Pubmed]
  26. Dose-dependent neurotoxicity of high-dose busulfan in children: a clinical and pharmacological study. Vassal, G., Deroussent, A., Hartmann, O., Challine, D., Benhamou, E., Valteau-Couanet, D., Brugières, L., Kalifa, C., Gouyette, A., Lemerle, J. Cancer Res. (1990) [Pubmed]
  27. Effects of long-term bosentan in children with pulmonary arterial hypertension. Rosenzweig, E.B., Ivy, D.D., Widlitz, A., Doran, A., Claussen, L.R., Yung, D., Abman, S.H., Morganti, A., Nguyen, N., Barst, R.J. J. Am. Coll. Cardiol. (2005) [Pubmed]
  28. The role of graft material in femorotibial bypass grafts. Edwards, W.H., Mulherin, J.L. Ann. Surg. (1980) [Pubmed]
  29. Diagnostic 131-iodine whole-body scan may be avoided in thyroid cancer patients who have undetectable stimulated serum Tg levels after initial treatment. Pacini, F., Capezzone, M., Elisei, R., Ceccarelli, C., Taddei, D., Pinchera, A. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  30. Hormone replacement therapy and interrelation between serum interleukin-6 and body mass index in postmenopausal women: a population-based study. Straub, R.H., Hense, H.W., Andus, T., Schölmerich, J., Riegger, G.A., Schunkert, H. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  31. Heparin treatment in sinus venous thrombosis. Einhäupl, K.M., Villringer, A., Meister, W., Mehraein, S., Garner, C., Pellkofer, M., Haberl, R.L., Pfister, H.W., Schmiedek, P. Lancet (1991) [Pubmed]
  32. A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993). Makin, A.J., Wendon, J., Williams, R. Gastroenterology (1995) [Pubmed]
  33. Neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency. Pourfarzam, M., Morris, A., Appleton, M., Craft, A., Bartlett, K. Lancet (2001) [Pubmed]
  34. Autoantibody screening in subacute cerebellar ataxia. Trivedi, R., Mundanthanam, G., Amyes, E., Lang, B., Vincent, A. Lancet (2000) [Pubmed]
  35. NIH conference. Recent advances in chronic granulomatous disease. Gallin, J.I., Buescher, E.S., Seligmann, B.E., Nath, J., Gaither, T., Katz, P. Ann. Intern. Med. (1983) [Pubmed]
  36. Correlation of KAI1/CD82 gene expression with good prognosis in patients with non-small cell lung cancer. Adachi, M., Taki, T., Ieki, Y., Huang, C.L., Higashiyama, M., Miyake, M. Cancer Res. (1996) [Pubmed]
  37. Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Ambrosone, C.B., Sweeney, C., Coles, B.F., Thompson, P.A., McClure, G.Y., Korourian, S., Fares, M.Y., Stone, A., Kadlubar, F.F., Hutchins, L.F. Cancer Res. (2001) [Pubmed]
  38. The RAS signal transduction pathway and its role in radiation sensitivity. McKenna, W.G., Muschel, R.J., Gupta, A.K., Hahn, S.M., Bernhard, E.J. Oncogene (2003) [Pubmed]
  39. Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer. Ishikawa, S., Takenaka, K., Yanagihara, K., Miyahara, R., Kawano, Y., Otake, Y., Hasegawa, S., Wada, H., Tanaka, F. Clin. Cancer Res. (2004) [Pubmed]
  40. Overexpression of matrix metalloproteinase-1 and -9 mRNA is associated with progression of oral dysplasia to cancer. Jordan, R.C., Macabeo-Ong, M., Shiboski, C.H., Dekker, N., Ginzinger, D.G., Wong, D.T., Schmidt, B.L. Clin. Cancer Res. (2004) [Pubmed]
  41. Long-term results of resection for large hepatocellular carcinoma: a multivariate analysis of clinicopathological features. Lai, E.C., Ng, I.O., Ng, M.M., Lok, A.S., Tam, P.C., Fan, S.T., Choi, T.K., Wong, J. Hepatology (1990) [Pubmed]
  42. Lymphovascular invasion is independently associated with overall survival, cause-specific survival, and local and distant recurrence in patients with negative lymph nodes at radical cystectomy. Lotan, Y., Gupta, A., Shariat, S.F., Palapattu, G.S., Vazina, A., Karakiewicz, P.I., Bastian, P.J., Rogers, C.G., Amiel, G., Perotte, P., Schoenberg, M.P., Lerner, S.P., Sagalowsky, A.I. J. Clin. Oncol. (2005) [Pubmed]
  43. Increased incidence of cervical atypia in women with systemic lupus erythematosus treated with chemotherapy. Nyberg, G., Eriksson, O., Westberg, N.G. Arthritis Rheum. (1981) [Pubmed]
  44. Gastric cancer detection in gastric ulcer disease. Mountford, R.A., Brown, P., Salmon, P.R., Alvarenga, C., Neumann, C.S., Read, A.E. Gut (1980) [Pubmed]
  45. Amiodarone therapy does not compromise subsequent heart transplantation. Chelimsky-Fallick, C., Middlekauff, H.R., Stevenson, W.G., Kobashigawa, J., Saxon, L.A., Moriguchi, J., Brownfield, E.D., Hamilton, M.A., Drinkwater, D., Laks, H. J. Am. Coll. Cardiol. (1992) [Pubmed]
WikiGenes - Universities