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Human proto-oncogene c-mos maps to 8q11.

The c-mos proto-oncogene is the cellular counterpart of the viral oncogene v-mos isolated from Moloney murine sarcoma virus. The c-mos gene locus has previously been assigned to human chromosome 8. By both in situ hybridization and molecular hydridization to sorted chromosome DNA (using a c-mos probe) we have localized the c-mos gene to band 8q11. This regional localization is at variance with the one previously reported at 8q22 and may explain why no rearrangement of c-mos has been found in acute leukaemia with the chromosomal translocation t(8;21)(q22;q22).[1]

References

  1. Human proto-oncogene c-mos maps to 8q11. Caubet, J.F., Mathieu-Mahul, D., Bernheim, A., Larsen, C.J., Berger, R. EMBO J. (1985) [Pubmed]
 
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