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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Mechanism of biosynthesis of 2-oxo-3-methylvalerate in Chlorobium vibrioforme.

The biosynthesis of 2-oxo-3-methylvalerate in Chlorobium vibrioforme was investigated by 13C nuclear magnetic resonance spectroscopy of the oxoacid formed from 13C-labeled acetate by washed suspensions. The threonine pathway could be excluded, and the results are in accord with a mechanism for the formation of 2-oxobutyrate from acetyl coenzyme A and pyruvate via citramalate.[1]

References

  1. Mechanism of biosynthesis of 2-oxo-3-methylvalerate in Chlorobium vibrioforme. Nesbakken, T., Kolsaker, P., Ormerod, J. J. Bacteriol. (1988) [Pubmed]
 
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