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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Protective immunity induced by outer membrane proteins of Salmonella typhimurium in mice.

Outer membrane proteins (OMP) extracted from both smooth (C5) and rough ( Rb2) strains of Salmonella typhimurium were able to induce protective immunity to salmonellosis. The OMP-induced protection lasted for at least 6 months. The antibody level was estimated by passive hemagglutination. In the C5 OMP-immunized mice, antibodies to both proteins and lipopolysaccharide were detected. On the other hand, in the Rb2 OMP-immunized mice, antiprotein but not antilipopolysaccharide antibodies were detected. Delayed-type hypersensitivity appeared as early as the second week after immunization with OMP and persisted through the fourth week.[1]

References

  1. Protective immunity induced by outer membrane proteins of Salmonella typhimurium in mice. Udhayakumar, V., Muthukkaruppan, V.R. Infect. Immun. (1987) [Pubmed]
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