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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Longterm treatment with brompheniramine and phenylpropanolamine in recurrent otitis media--a double-blind study.

A double-blind study has been performed in 44 children with recurrent episodes of otitis media and/or secretory otitis media using a combined preparation of brompheniraminemaleate and phenylpropanolaminehydrocloride (Lunerin mite). No significant prophylactic effect was found on symptoms of respiratory tract infections or middle ear diseases during the trial period of nine months. The result suggests that further critical studies should be performed with such preparations which for the time being are used abundantly for the prevention of middle ear infections or effusions.[1]

References

  1. Longterm treatment with brompheniramine and phenylpropanolamine in recurrent otitis media--a double-blind study. Kjellman, N.I., Harder, H., Lindwall, L., Synnerstad, B. The Journal of otolaryngology. (1978) [Pubmed]
 
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