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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Mathematical model of muscular fatigue. Part III. Classification of muscular fibres versus metabolism of exhaustion.

In order to modelize muscular fatigue, use and depletion of energizing stores are incorporated in the previously elaborated model. The role of muscle glycogen is crucial in sustained muscular contractions. Two patterns of muscular exhaustion are described: one is related to glycogen depletion (S and FR fibres) and the other to an unphysiological drop in ATP concentrations (FF fibres). Thus, the muscle fibre recruitment can be related to its theoretical metabolism of exhaustion. The importance of the muscle lactate level is connected to the glucose entry into the muscle cell and the rigor mortis. Computations have been carried out on a computer DPS 7.[1]

References

  1. Mathematical model of muscular fatigue. Part III. Classification of muscular fibres versus metabolism of exhaustion. Valentini, F.A., Nelson, P.P. Int. J. Biomed. Comput. (1986) [Pubmed]
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