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Hypoxanthine and adenine metabolism in bovine thyroid tissue.

Hypoxanthine was converted primarily to uric acid by thyroid tissue slices and homogenates with little inosine 5'-monophosphate formation while adenine was essentially all salvaged to adenosine 5'-monophosphate by similar tissue preparations. The ratio of hypoxanthine/guanine phosphoribosyltransferase activity to adenine phosphoribosyltransferase activity was 0.15 in the thyroid homogenates.[1]

References

  1. Hypoxanthine and adenine metabolism in bovine thyroid tissue. Post, G.R., Fischer, A.G. Int. J. Biochem. (1986) [Pubmed]
 
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