The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The engrailed locus of D. melanogaster provides an essential zygotic function in precellular embryos.

Early embryonic development in Drosophila depends on genes expressed during oogenesis or after zygote formation. We show that the engrailed gene is needed for the processes that organize the embryo during the nuclear divisions that precede cellularization. During the precellular blastoderm stages engrailed mutant embryos show several notable anomalies: the pole cells form at a position slightly displaced from the posterior pole; yolk nuclei continue to divide after the tenth nuclear division cycle, when wild-type yolk nuclei have stopped dividing mitotically; and somatic nuclei are not positioned uniformly along the embryo periphery and do not undergo mitotic divisions in regular waves. This early requirement for engrailed does not appear to be a maternal function, and only genetically engrailed embryos displayed these precellular phenotypes. Synthesis of a 2.7 kb poly(A)+ transcript of the engrailed region was found in precellular embryos.[1]


WikiGenes - Universities