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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Induction of labor in the high-risk pregnancy with PGF 2 alpha.

The induction of labor in the high-risk patient is accompanied by an increased incidence of cesarean section partly due to failed induction. A series of 50 high-risk patients induced with intravenous prostaglandin F 2 alpha is presented. Forty-five were successfully induced, 35 of whom delivered vaginally. Failed inductions occurred in 5 patients. The overall success rate was 90%, and cesarean section rate was 25.5%. There was an increased incidence of late decelerations in the PGF 2 alpha groups as compared to spontaneous and Pitocin-stimulated labors. While the success was high, the use of a drug which itself may caused fetal cardiovascular changes is not desirable, especially in those pregnancies already at risk.[1]

References

  1. Induction of labor in the high-risk pregnancy with PGF 2 alpha. O'Sullivan, M.J., Stone, M.L., Gugliucci, C.L., Shah, G., Stephens, M.L. Obstetrics and gynecology. (1978) [Pubmed]
 
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