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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Venereal transmission of La Crosse virus from male to female Aedes triseriatus.

Horizontal transmission of La Crosse ( LAC) arbovirus in colonized Aedes triseriatus was first observed in mating cages. LAC antigen was visualized by fluorescent antibody technique in multiple organs of 5 (2.5% of 198 females dissected after contact in mating cages with males, with a transovarial infection rate of 31%. Venereal transmission of LAC virus was demonstrated by limited contact induced mating. Antigen was detected in bursal contents of 35 (53%) of 66 females dissected within 24 h after induced mating by males previously infected by intrathoracic inoculation. Antigen was observed in ovaries, heart, gut, salivary glands, or other organs in 13 (3.4%) of 379 females dissected 1 to 14 days post-mating. LAC virus was isolated from infected males, from contents of the bursa copulatrix of females following mating, and from dissection remnants of 6 of the 13 females in which disseminated antigen had been observed. Venereally infected females were shown to be capable of transmission of LAC virus by bite to mice and to eggs.[1]


  1. Venereal transmission of La Crosse virus from male to female Aedes triseriatus. Thompson, W.H., Beaty, B.J. Am. J. Trop. Med. Hyg. (1978) [Pubmed]
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