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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Apparent ketoconazole failure in candidal cholecystitis.

Fungal acalculous cholecystitis is a rarely recognized complication of disseminated candidal infections. We report such a case of systemic candidiasis that developed in a man who was diabetic while he was receiving broad-spectrum antibiotic therapy for an infected foot ulcer. Ketoconazole, a new imidazole antifungal agent, was used successfully to treat the systemic candidal infection but it failed to eradicate the fungus in the biliary tract.[1]


  1. Apparent ketoconazole failure in candidal cholecystitis. Brooks, B.J., Williams, W.L., Sanders, C.V., Marier, R.L. Arch. Intern. Med. (1982) [Pubmed]
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