The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Mutagen formation in browning model systems.

A browning model system, consisting of diacetyl and ammonia, produced frameshift and base-pair substitution mutagens when the system was heated over 20 min and 120 min, respectively. The major product was 2,4,5- trimethylimidazole , which showed no mutagenicity toward Salmonella typhimurium strains TA98 and TA100 with or without metabolic activation. When furfural was reacted with nitrate under mild conditions (for 30 min to 3 h at 0-25 degrees C and pH 2-7), it did not produce mutagenic nitrofuran derivatives. However, the ethyl ether extract obtained from the reaction mixture of furfural and nitrate with hydrochloric acid exhibited strong mutagenic activities toward S. typhimurium strains TA98 and TA100 in the presence of metabolic activation. The major product of this reaction mixture, 4- nitrofurfural , exhibited no mutagenicity toward tester strains TA98 and TA100 with or without metabolic activation. Pure active mutagen(s) was (were) not, however, identified in either system.[1]


  1. Mutagen formation in browning model systems. Shibamoto, T. Journal of applied toxicology : JAT. (1984) [Pubmed]
WikiGenes - Universities