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Chemical Compound Review

ether     ethoxyethane

Synonyms: Pronarcol, Aether, Ethylether, DIETHYLETHER, Ethoxyethane, ...
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Disease relevance of DIETHYL ETHER


Psychiatry related information on DIETHYL ETHER


High impact information on DIETHYL ETHER

  • Apoprotein E, isolated after delipidization of lipoproteins with either methyl ethyl ketone or ethanol and ethyl ether, was immunosuppressive [7].
  • Thus, erythromycin B enol ether ethyl succinate is very poorly soluble in water, and its hydrolysis is undetectable in conditions resembling the medicine bottle [8].
  • Reaction of adenosine with an excess of BM in phosphate buffer (pH 7.4) at 37 degrees C, followed by extraction of the reaction mixture with ethyl ether to remove excess unreacted BM and incubation at 80 degrees C for 1 h, resulted in complete conversion of N1-adenosine adducts to the corresponding N6-adenosine and N1-inosine adducts [9].
  • Tracheal epithelium of mice anesthetized with ethyl ether was studied in the electron microscope with the techniques of thin sectioning and freeze fracture [10].
  • After acidification of the reaction medium, the products were extracted with ethyl ether, converted to their methyl esters, and characterized using HPLC [11].

Chemical compound and disease context of DIETHYL ETHER


Biological context of DIETHYL ETHER


Anatomical context of DIETHYL ETHER


Associations of DIETHYL ETHER with other chemical compounds


Gene context of DIETHYL ETHER

  • Via the in vitro PLA2 inhibitor assay, it was shown that the ethyl ether extract of the medium contained significant PLA2 inhibitor activity [29].
  • Amebic cysteine protease 2 (EhCP2) was purified from ethyl ether extracts of axenically grown trophozoites of Entamoeba histolytica strain HM1-IMSS [30].
  • The sensitive component induced by f(2) levels below 65 dB SPL is selectively affected by application of ethyl ether and disappears more quickly than the high-level component during ongoing deterioration of the moth preparation [31].
  • Two experimental designs were used: First, either 12.5, 25 or 50 micrograms ethyleneglycol-bis-(beta-amino ethyl ether) N,N'-tetra-acetic acid (EGTA), or 25 or 50 micrograms verapamil, both dissolved in an artificial CSF vehicle, were infused ICV at the same time as ethanol's administration [32].
  • The biodegradation sequence of the target compounds by the mixed culture, in order of removal rate, was toluene, ethyl benzene, p-xylene, benzene, MTBE, ethyl ether, tert-amyl methyl ether, and ethyl tert-butyl ether [33].

Analytical, diagnostic and therapeutic context of DIETHYL ETHER


  1. Malignant lymphoma induction in rabbits by intravenous inoculation of Epstein-Barr-virus-related herpesvirus from HTLV-II-transformed cynomolgus leukocyte cell line (Si-IIA). Hayashi, K., Koirala, T.R., Ino, H., Chen, H.L., Ohara, N., Teramoto, N., Yoshino, T., Takahashi, K., Yamada, M., Nii, S. Int. J. Cancer (1995) [Pubmed]
  2. Thermal chemistry of podophyllotoxin in ethanol and a comparison of the cytostatic activity of the thermolysis products. Buchardt, O., Jensen, R.B., Hansen, H.F., Nielsen, P.E., Andersen, D., Chinoin, I. Journal of pharmaceutical sciences. (1986) [Pubmed]
  3. Short-term oral toxicity of butyl ether, ethyl hexyl ether, methyl heptyl ether and 1,6-dimethoxyhexane in male rats and the role of 2-methoxyacetic acid. Poon, R., Wade, M., Valli, V.E., Chu, I. Toxicology (2005) [Pubmed]
  4. Hair lotion dermatitis with sensitization to d-panthenyl ethyl ether. van Ketel, W.G. Contact Derm. (1984) [Pubmed]
  5. Relationships between spleen and respiration in the newt. Frangioni, G., Borgioli, G. J. Exp. Zool. (1989) [Pubmed]
  6. Neonatal inhalatory anesthetic exposure: reproductive changes in male rats. Arena, A.C., Pereira, O.C. Comp. Biochem. Physiol. C Toxicol. Pharmacol. (2002) [Pubmed]
  7. Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein, LDL-In. Pepe, M.G., Curtiss, L.K. J. Immunol. (1986) [Pubmed]
  8. Design, synthesis, and evaluation of stable and taste-free erythromycin proprodrugs. Bhadra, P.K., Morris, G.A., Barber, J. J. Med. Chem. (2005) [Pubmed]
  9. Characterization of N1- and N6-adenosine adducts and N1-inosine adducts formed by the reaction of butadiene monoxide with adenosine: evidence for the N1-adenosine adducts as major initial products. Selzer, R.R., Elfarra, A.A. Chem. Res. Toxicol. (1996) [Pubmed]
  10. A correlated thin section and freeze-fracture study of mouse tracheal epithelium before and after ether anesthesia. Inoue, S., Richardson, J.B. Lab. Invest. (1979) [Pubmed]
  11. Isolation of unsaturated diols after oxidation of conjugated linoleic acid with peroxygenase. Piazza, G.J., Nuñez, A., Foglia, T.A. Lipids (2003) [Pubmed]
  12. alpha, beta-Arteether for the treatment of complicated falciparum malaria. Mohanty, S., Mishra, S.K., Satpathy, S.K., Dash, S., Patnaik, J. Trans. R. Soc. Trop. Med. Hyg. (1997) [Pubmed]
  13. Purification and characterization of a signal peptide, a product of protein secretion across the cytoplasmic membrane of Escherichia coli. Suzuki, T., Ichihara, S., Mizushima, S. J. Biochem. (1988) [Pubmed]
  14. Corrections of prooxidant-antioxidant homeostasis of organism under hypoxia of different genesis by yackton, a new pharmacological preparation. Gonchar, O., Klyuchko, E., Seredenko, M., Oliynik, S. Acta physiologica et pharmacologica Bulgarica. (2003) [Pubmed]
  15. Tetany: quantitative interrelationships between calcium and alkalosis. Edmondson, J.W., Brashear, R.E., Li, T.K. Am. J. Physiol. (1975) [Pubmed]
  16. Conversion of retinoid ethers to alcohols by enzymatic activity present in rat liver microsomes. Shih, T.W., Shealy, Y.F., Hill, D.L. Drug Metab. Dispos. (1991) [Pubmed]
  17. Mutagen formation in browning model systems. Shibamoto, T. Journal of applied toxicology : JAT. (1984) [Pubmed]
  18. Effects of inhalation of ethyl-ether on glycemia and on some variables of intermediate metabolism in rats. Pérez-Llamas, F., Zamora, S., Rosique, M.J., Sastre, J.F. Archives internationales de physiologie, de biochimie et de biophysique. (1992) [Pubmed]
  19. Effects of chronic experimental alcoholism on the epithelium of the uterine horn of rats (Rattus norvegicus albinus). Martinez, M., Garcia, P.J., Cagnon, V.H., Mello-Júnior, W., Padovani, C.R., Martinez, F.E. J. Submicrosc. Cytol. Pathol. (2001) [Pubmed]
  20. Ethyl-oxide effects on a newly formed blood-brain barrier. Nico, B., Ribatti, D., Bertossi, M., Mancini, L., Roncali, L. J. Submicrosc. Cytol. Pathol. (1989) [Pubmed]
  21. Partial purification and characterization of a triacyglycerol lipase from rat liver cytosol. Toshima, K., Nakaya, Y., Matsumura, S., Nishizuka, Y. Biochim. Biophys. Acta (1977) [Pubmed]
  22. Antioxidant and anticancer activities of organic extracts from Platycodon grandiflorum A. De Candolle roots. Lee, J.Y., Hwang, W.I., Lim, S.T. Journal of ethnopharmacology. (2004) [Pubmed]
  23. Antidiuretic peptide in mammalian choroid plexus. Rudman, D., Chawla, R.K. Am. J. Physiol. (1976) [Pubmed]
  24. Inhibitors of sterol synthesis: synthesis and spectral properties of derivatives of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one fluorinated at carbon 7 or carbon 9 and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells. Siddiqui, A.U., Swaminathan, S., Pinkerton, F.D., Gerst, N., Wilson, W.K., Choi, H., Schroephfer, G.J. Chem. Phys. Lipids (1994) [Pubmed]
  25. Pharmacokinetic, biliary excretion, and metabolic studies of 14C-furosemide in the rat. Prandota, J., Pruitt, A.W. Xenobiotica (1991) [Pubmed]
  26. Validated method for quantitation and identification of 4,4-desmethylsterols and triterpene diols in plant oils by thin-layer chromatography-high resolution gas chromatography-mass spectrometry. Reina, R.J., White, K.D., Jahngen, E.G. Journal of AOAC International. (1997) [Pubmed]
  27. A method for the estimation of amino acid radioactivity in biological samples. Pons, A., García, F.J., Palou, A., Alemany, M. J. Biochem. Biophys. Methods (1981) [Pubmed]
  28. Simultaneous determination of all-trans-, 13-cis-, 9-cis-retinoic acid and their 4-oxo-metabolites in plasma by high-performance liquid chromatography. Disdier, B., Bun, H., Catalin, J., Durand, A. J. Chromatogr. B, Biomed. Appl. (1996) [Pubmed]
  29. Xenorhabdus nematophilus inhibits p-bromophenacyl bromide (BPB)-sensitive PLA2 of Spodoptera exigua. Park, Y., Kim, Y. Arch. Insect Biochem. Physiol. (2003) [Pubmed]
  30. Amebic cysteine proteinase 2 (EhCP2) plays either a minor or no role in tissue damage in acute experimental amebic liver abscess in hamsters. Olivos-García, A., González-Canto, A., López-Vancell, R., García de León, M.d.e.l. .C., Tello, E., Nequiz-Avendaño, M., Montfort, I., Pérez-Tamayo, R. Parasitol. Res. (2003) [Pubmed]
  31. Components of the 2f(1)-f(2) distortion-product otoacoustic emission in a moth. Coro, F., Kössl, M. Hear. Res. (2001) [Pubmed]
  32. Alcohol-induced poikilothermia, sleep and motor impairment: actions on brain of EGTA and verapamil. Paez, X., Myers, R.D. Alcohol (1989) [Pubmed]
  33. Effects of environmental settings on MTBE removal for a mixed culture and its monoculture isolation. Lin, C.W., Tsai, S.L., Hou, S.N. Appl. Microbiol. Biotechnol. (2007) [Pubmed]
  34. Elucidation of chemical compounds responsible for foot malodour. Kanda, F., Yagi, E., Fukuda, M., Nakajima, K., Ohta, T., Nakata, O. Br. J. Dermatol. (1990) [Pubmed]
  35. Oocyte fertilization in vitro is associated with high follicular immunoreactive beta-endorphin levels. Facchinetti, F., Artini, P.G., Monaco, M., Volpe, A., Genazzani, A.R. J. Endocrinol. Invest. (1989) [Pubmed]
  36. Norgestimate increases pituitary and hypothalamic concentrations of immunoreactive beta-endorphin. Genazzani, A.R., Petraglia, F., Cleva, M., Brilli, G., Mercuri, N., De Ramundo, B.M., Volpe, A. Contraception. (1989) [Pubmed]
  37. Liquid chromatographic determination of rotenone in fish, crayfish, mussels, and sediments. Dawson, V.K., Allen, J.L. Journal - Association of Official Analytical Chemists. (1988) [Pubmed]
  38. The anxiolytic-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice. Hellión-Ibarrola, M.C., Ibarrola, D.A., Montalbetti, Y., Kennedy, M.L., Heinichen, O., Campuzano, M., Tortoriello, J., Fernández, S., Wasowski, C., Marder, M., De Lima, T.C., Mora, S. Journal of ethnopharmacology. (2006) [Pubmed]
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