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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Granulomatous hepatitis and cholangitis associated with giardiasis.

Biopsy of the liver revealed granulomas in portal tracts and cholangitis in a woman with chronic diarrhea, weight loss, fever, hypoalbuminemia, and anemia attributed to giardiasis. Eradication of Giardia resulted in rapid improvement of symptoms and resolution of histologic changes on a second biopsy of the liver after 3 mo. The patient had serum immunoglobulin levels that were either normal (IgG, IgM) or elevated (IgA), detectable levels in serum of anti-Giardia antibody, and an HLA phenotype ( B12, B27) known to be associated with prolonged giardiasis.[1]

References

  1. Granulomatous hepatitis and cholangitis associated with giardiasis. Roberts-Thomson, I.C., Anders, R.F., Bhathal, P.S. Gastroenterology (1982) [Pubmed]
 
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