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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Polydipsia and abolition of angiotensin-induced drinking after transections of subfornical organ efferent projections in the rat.

Rats with transections of subfornical organ (SFO) efferent projections failed to drink to intravenous angiotensin-II (AII) but responded to intracellular dehydration and water deprivation and suppressed drinking when food deprived. However, the transected rats were polydipsic and polyuric. Thus SFO efferent projections mediate AII-induced drinking and may be involved in the regulation of body fluid balance.[1]


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