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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sympathetic ganglion blockade for the management of hyperhidrosis.

We present three patients with severe primary hyperhidrosis, refractory to conservative medical treatment, who were successfully managed with sympathetic ganglion blockade with ethanol. We also summarize 10 patients with hyperhidrosis who underwent sympathetic ganglion blockade in the past 2 years. This closed percutaneous method offers the patients considerably less discomfort and less stress with minimal morbidity and has a efficacy similar to that of surgical sympathectomy, which has previously been the only effective and permanent therapy for severe primary hyperhidrosis. It is concluded that chemical sympathectomy is an effective and useful method for treating severe hyperhidrosis which has advantages over surgical sympathectomy.[1]


  1. Sympathetic ganglion blockade for the management of hyperhidrosis. Kobayashi, K., Omote, K., Homma, E., Abe, T., Iitoyo, M. J. Dermatol. (1994) [Pubmed]
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