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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Tumor necrosis factor, interleukin-2, and interferon-gamma in adult varicella.

Adult varicella can be a severe illness complicated by pneumonia, encephalitis, or prolonged fever. This study measured levels of tumor necrosis factor (TNF)-alpha, interleukin-2 (IL-2), and interferon gamma (IFN-G) in a consecutive group of 31 adult varicella patients presenting within 24 hours of rash onset. All cytokines were assayed using an ELISA technique. TNF-alpha was detectable in 71% of patients with a mean level of 52 pg/ml. IL-2 was detectable in 29% with a mean level of 1040 pg/ml. IFN-gamma was detectable in only 9%. There was no correlation between TNF, IL-2, or IFN-G level and clinical severity as determined by duration and severity of cutaneous findings, duration of fever, frequency of hepatitis, or thrombocytopenia.[1]

References

  1. Tumor necrosis factor, interleukin-2, and interferon-gamma in adult varicella. Wallace, M.R., Woelfl, I., Bowler, W.A., Olson, P.E., Murray, N.B., Brodine, S.K., Oldfield, E.C., Arvin, A.M. J. Med. Virol. (1994) [Pubmed]
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