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MeSH Review

Encephalitis

 
 
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Disease relevance of Encephalitis

 

Psychiatry related information on Encephalitis

 

High impact information on Encephalitis

 

Chemical compound and disease context of Encephalitis

 

Biological context of Encephalitis

 

Anatomical context of Encephalitis

 

Gene context of Encephalitis

 

Analytical, diagnostic and therapeutic context of Encephalitis

  • After intradermal vaccination with live recombinant virus expressing the G protein, mice produced VSV-neutralizing antibodies and were protected against lethal encephalitis upon intravenous challenge with VSV [34].
  • The exact mechanism of this age-related susceptibility to brain inflammation has yet to be defined, but animal models have revealed that the potent pro-inflammatory cytokine interleukin-1beta (IL-1beta) initiates an intense acute neutrophil-mediated inflammatory response in the brains of young rats and mice that is not seen in adults [6] [35].
  • In situ hybridization for SIV and proliferating cellular nuclear antigen (PCNA) immunohistochemistry demonstrated that SIV-infected and PCNA-positive cells were predominantly found in perivascular cuffs of viremic animals and in histopathological lesions that characterize SIV encephalitis (SIVE) in animals with AIDS [36].
  • As an in vivo model of encephalitis, wild-type or TLR3(-/-) mice were injected intracerebroventricularly with poly(I:C) or LPS, and microglial activation was assessed by cell surface marker or phospho-MAPK immunofluorescence [37].
  • Objective: To determine the associations between HIV encephalitis and other central nervous system (CNS) pathology, viral burden, cognitive impairment, zidovudine therapy and risk group in AIDS patients [38].

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  25. The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity. Xu, J., Wang, P., Li, Y., Li, G., Kaczmarek, L.K., Wu, Y., Koni, P.A., Flavell, R.A., Desir, G.V. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
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