The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effects of Phytolacca acinosa polysaccharides I on immune function in mice.

Radioactivities of [3H]TdR uptaken by splenocytes and released from [3H]TdR-labeled YAC-1 cell line were measured to determine the degree of lymphocyte proliferation and natural killer (NK) cell activity. Seven days after mice treated with Phytolacca acinosa polysaccharides I (PAP-I) 5-50, the NK cell activity, and lymphocyte proliferation induced by Con A 5 or lipopolysaccharides 10 were significantly augmented. Splenocytes from mice treated with ip PAP-I 5-50 were incubated with Con A 5 for 24 h to induce interleukin-2 (IL-2) and for 40 h to induce NK cytotoxic factor (NKCF). Radioactivities of [3H]TdR uptaken by CTLL-2 cell line and YAC-1 cell line were used to measure the IL-2 and NKCF activities, respectively. PAP-I enhanced the production of IL-2 and NKCF. These results suggest that PAP-I augments the immunological functions in vivo.[1]


  1. Effects of Phytolacca acinosa polysaccharides I on immune function in mice. Wang, H.B., Zheng, Q.Y., Qian, D.H., Fang, J., Ju, D.W. Zhongguo yao li xue bao = Acta pharmacologica Sinica. (1993) [Pubmed]
WikiGenes - Universities