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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Hepatic veno-occlusive disease due to pyrrolizidine (Senecio) poisoning in Arizona.

An infant with documented hepatic veno-occlusive disease due to ingestion of pyrrolizidine alkaloids is presented. The alkaloids were ingested in the form of an herbal tea commonly used as a folk remedy among the Mexican-American population. Among these people, this herb is known as gordolobo yerba. The patient presented with acute hepatocellular disease and portal hypertension which progressed over 2 months to extensive hepatic fibrosis. Other potential causes of hepatic venous occlusion were absent.[1]


  1. Hepatic veno-occlusive disease due to pyrrolizidine (Senecio) poisoning in Arizona. Stillman, A.S., Huxtable, R., Consroe, P., Kohnen, P., Smith, S. Gastroenterology (1977) [Pubmed]
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