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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Hepatoprotective effects of emodin from Ventilago leiocarpa.

A major component of ethyl acetate (EtOAc) and chloroform (CHCl3) fractions of Ventilago leiocarpa Bunge (Rhamnaceae), emodin, was isolated and exhibited hepatoprotective effects on carbon tetrachloride (CCl4) as well as D-galactosamine (D-GalN)-induced liver damage. The histopathological examination also clearly showed that emodin reduced lymphocyte cells, Kupffer cells, ballooning degeneration, cell necrosis and hyaline degeneration on CCl4 and D-galactosamine-induced tests.[1]


  1. Hepatoprotective effects of emodin from Ventilago leiocarpa. Lin, C.C., Chang, C.H., Yang, J.J., Namba, T., Hattori, M. Journal of ethnopharmacology. (1996) [Pubmed]
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