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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Cryptococcal meningitis in a child with hyperimmunoglobulin E syndrome.

A 13-year-old boy with hyperimmunoglobulin E (hyper-IgE) syndrome presented with headache, blurred vision, photophobia and bilateral papilledema due to cryptococcal meningitis. Treatment with amphotericin B, and S-fluorocytosine for several weeks and repeated lumbar punctures did not reduce the intracranial pressure, and a myeloperitoneal shunt was performed. The child was maintained on fluconazole for an additional six months. Patients with hyper-IgE syndrome are at increased risk of opportunistic fungal infections such as cryptococcal meningitis.[1]

References

  1. Cryptococcal meningitis in a child with hyperimmunoglobulin E syndrome. Garty, B.Z., Wolach, B., Ashkenazi, S., Weismart, Y., Rachmel, A., Nitzan, M. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. (1995) [Pubmed]
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