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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Thyroid carcinoma as first manifestation of familial adenomatous polyposis.

A 22-year-old female member of a family with familial adenomatous polyposis ( FAP) presented with a thyroid nodule. Histology revealed a follicular carcinoma. The patient was on regular follow-up as part of the FAP screening program; 1.5 years after the thyroidectomy she appeared to have multiple adenomatous polyps in her colon and FAP was diagnosed. Thyroid-carcinoma is one of the extraintestinal manifestations of FAP and particularly women in the age of 25-35 years are at risk according to the literature.[1]


  1. Thyroid carcinoma as first manifestation of familial adenomatous polyposis. Stigt, J.A., Vasen, H.F., van der Linde, K., van Vliet, A.C. The Netherlands journal of medicine. (1996) [Pubmed]
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