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MeSH Review

Adenomatous Polyposis Coli

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Disease relevance of Adenomatous Polyposis Coli


Psychiatry related information on Adenomatous Polyposis Coli


High impact information on Adenomatous Polyposis Coli


Chemical compound and disease context of Adenomatous Polyposis Coli


Biological context of Adenomatous Polyposis Coli


Anatomical context of Adenomatous Polyposis Coli


Gene context of Adenomatous Polyposis Coli


Analytical, diagnostic and therapeutic context of Adenomatous Polyposis Coli


  1. Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors. Al-Tassan, N., Chmiel, N.H., Maynard, J., Fleming, N., Livingston, A.L., Williams, G.T., Hodges, A.K., Davies, D.R., David, S.S., Sampson, J.R., Cheadle, J.P. Nat. Genet. (2002) [Pubmed]
  2. The molecular basis of Turcot's syndrome. Hamilton, S.R., Liu, B., Parsons, R.E., Papadopoulos, N., Jen, J., Powell, S.M., Krush, A.J., Berk, T., Cohen, Z., Tetu, B. N. Engl. J. Med. (1995) [Pubmed]
  3. Localization of the gene for familial adenomatous polyposis on chromosome 5. Bodmer, W.F., Bailey, C.J., Bodmer, J., Bussey, H.J., Ellis, A., Gorman, P., Lucibello, F.C., Murday, V.A., Rider, S.H., Scambler, P. Nature (1987) [Pubmed]
  4. Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers. Sinicrope, F.A., Lemoine, M., Xi, L., Lynch, P.M., Cleary, K.R., Shen, Y., Frazier, M.L. Gastroenterology (1999) [Pubmed]
  5. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Labayle, D., Fischer, D., Vielh, P., Drouhin, F., Pariente, A., Bories, C., Duhamel, O., Trousset, M., Attali, P. Gastroenterology (1991) [Pubmed]
  6. Two cases of 5q deletions in patients with familial adenomatous polyposis: possible link with Caroli's disease. Hodgson, S.V., Coonar, A.S., Hanson, P.J., Cottrell, S., Scriven, P.N., Jones, T., Hawley, P.R., Wilkinson, M.L. J. Med. Genet. (1993) [Pubmed]
  7. Quality of life after total colectomy with ileorectal anastomosis or proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis. Van Duijvendijk, P., Slors, J.F., Taat, C.W., Oosterveld, P., Sprangers, M.A., Obertop, H., Vasen, H.F. The British journal of surgery. (2000) [Pubmed]
  8. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. Steinbach, G., Lynch, P.M., Phillips, R.K., Wallace, M.H., Hawk, E., Gordon, G.B., Wakabayashi, N., Saunders, B., Shen, Y., Fujimura, T., Su, L.K., Levin, B. N. Engl. J. Med. (2000) [Pubmed]
  9. Molecular linkage underlying microtubule orientation toward cortical sites in yeast. Korinek, W.S., Copeland, M.J., Chaudhuri, A., Chant, J. Science (2000) [Pubmed]
  10. Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. Hardwick, J.C., Van Den Brink, G.R., Bleuming, S.A., Ballester, I., Van Den Brande, J.M., Keller, J.J., Offerhaus, G.J., Van Deventer, S.J., Peppelenbosch, M.P. Gastroenterology (2004) [Pubmed]
  11. High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis. Venesio, T., Molatore, S., Cattaneo, F., Arrigoni, A., Risio, M., Ranzani, G.N. Gastroenterology (2004) [Pubmed]
  12. Sulindac in familial adenomatous polyposis. Labayle, D., Boyer, J., Drouhin, F., Zarka, Y., Fischer, D. Lancet (1994) [Pubmed]
  13. Gene modulation by the cyclooxygenase inhibitor, sulindac sulfide, in human colorectal carcinoma cells: possible link to apoptosis. Bottone, F.G., Martinez, J.M., Collins, J.B., Afshari, C.A., Eling, T.E. J. Biol. Chem. (2003) [Pubmed]
  14. The zebrafish retinol dehydrogenase, rdh1l, is essential for intestinal development and is regulated by the tumor suppressor adenomatous polyposis coli. Nadauld, L.D., Shelton, D.N., Chidester, S., Yost, H.J., Jones, D.A. J. Biol. Chem. (2005) [Pubmed]
  15. Caffeine phenotyping of cytochrome P4501A2, N-acetyltransferase, and xanthine oxidase in patients with familial adenomatous polyposis. Spigelman, A.D., Farmer, K.C., Oliver, S., Nugent, K.P., Bennett, P.N., Notarianni, L.J., Dobrocky, P., Phillips, R.K. Gut (1995) [Pubmed]
  16. Wheat bran fiber and development of adenomatous polyps: evidence from randomized, controlled clinical trials. Macrae, F. Am. J. Med. (1999) [Pubmed]
  17. Small changes in expression affect predisposition to tumorigenesis. Yan, H., Dobbie, Z., Gruber, S.B., Markowitz, S., Romans, K., Giardiello, F.M., Kinzler, K.W., Vogelstein, B. Nat. Genet. (2002) [Pubmed]
  18. The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis. Lamlum, H., Ilyas, M., Rowan, A., Clark, S., Johnson, V., Bell, J., Frayling, I., Efstathiou, J., Pack, K., Payne, S., Roylance, R., Gorman, P., Sheer, D., Neale, K., Phillips, R., Talbot, I., Bodmer, W., Tomlinson, I. Nat. Med. (1999) [Pubmed]
  19. Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC gene mutation. Giardiello, F.M., Krush, A.J., Petersen, G.M., Booker, S.V., Kerr, M., Tong, L.L., Hamilton, S.R. Gastroenterology (1994) [Pubmed]
  20. Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse. Scott, D.J., Hull, M.A., Cartwright, E.J., Lam, W.K., Tisbury, A., Poulsom, R., Markham, A.F., Bonifer, C., Coletta, P.L. Gastroenterology (2001) [Pubmed]
  21. Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis. Takeda, H., Sonoshita, M., Oshima, H., Sugihara, K., Chulada, P.C., Langenbach, R., Oshima, M., Taketo, M.M. Cancer Res. (2003) [Pubmed]
  22. Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice. Oshima, H., Oshima, M., Kobayashi, M., Tsutsumi, M., Taketo, M.M. Cancer Res. (1997) [Pubmed]
  23. Intestinal tumor progression is associated with altered function of KLF5. Bateman, N.W., Tan, D., Pestell, R.G., Black, J.D., Black, A.R. J. Biol. Chem. (2004) [Pubmed]
  24. Proliferative compartment deregulation in the non-neoplastic colonic epithelium of familial adenomatous polyposis. Mills, S.J., Shepherd, N.A., Hall, P.A., Hastings, A., Mathers, J.C., Gunn, A. Gut (1995) [Pubmed]
  25. Divergent effects of epidermal growth factor and calcipotriol on human rectal cell proliferation. Thomas, M.G., Brown, G.R., Alison, M.R., Williamson, R.C. Gut (1994) [Pubmed]
  26. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis. Li, Q., Ishikawa, T.O., Oshima, M., Taketo, M.M. Cancer Res. (2005) [Pubmed]
  27. Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients. Inomata, M., Ochiai, A., Akimoto, S., Kitano, S., Hirohashi, S. Cancer Res. (1996) [Pubmed]
  28. Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. Boolbol, S.K., Dannenberg, A.J., Chadburn, A., Martucci, C., Guo, X.J., Ramonetti, J.T., Abreu-Goris, M., Newmark, H.L., Lipkin, M.L., DeCosse, J.J., Bertagnolli, M.M. Cancer Res. (1996) [Pubmed]
  29. Cyclin D1 is not an essential target of beta-catenin signaling during intestinal tumorigenesis, but it may act as a modifier of disease severity in multiple intestinal neoplasia (Min) mice. Wilding, J., Straub, J., Bee, J., Churchman, M., Bodmer, W., Dickson, C., Tomlinson, I., Ilyas, M. Cancer Res. (2002) [Pubmed]
  30. Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. Cruz-Correa, M., Hylind, L.M., Romans, K.E., Booker, S.V., Giardiello, F.M. Gastroenterology (2002) [Pubmed]
  31. Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis. Giardiello, F.M., Casero, R.A., Hamilton, S.R., Hylind, L.M., Trimbath, J.D., Geiman, D.E., Judge, K.R., Hubbard, W., Offerhaus, G.J., Yang, V.W. Gastroenterology (2004) [Pubmed]
  32. Non-penetrance and late appearance of polyps in families with familial adenomatous polyposis. Evans, D.G., Guy, S.P., Thakker, N., Armstrong, J.G., Dodd, C., Davies, D.R., Babbs, C., Clancy, T., Warnes, T., Sloan, P. Gut (1993) [Pubmed]
  33. DNA aneuploidy and cell proliferation in familial adenomatous polyposis. Quirke, P., Dixon, M.F., Day, D.W., Fozard, J.B., Talbot, I.C., Bird, C.C. Gut (1988) [Pubmed]
  34. Appearances can be deceptive: an APC 1893del4 mutation with unusual properities. Mutations in brief no. 171. Online. Frayling, I.M., Armstrong, J.G., Davies, D.R., Evans, D.G., Guy, S.P. Hum. Mutat. (1998) [Pubmed]
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