- Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome. Fergusson, J., Landon, M., Lowe, J., Dawson, S.P., Layfield, R., Hanger, D.P., Mayer, R.J. Neurosci. Lett. (1996)