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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Immunohistochemical localization of calbindin D28k in the periodontal Ruffini endings of rat incisors.

It was examined whether calbindin D28k ( CB) might be located in the rat incisor periodontal Ruffini ending, an essential mechanoreceptor in periodontal ligament, by light- and electron-microscopic immunohistochemistry. Some thick nerve fibers showing CB-like immunoreactivity (LI) entered the lingual half of the periodontal ligament of the incisor and showed the dendritic terminal arborization. Electron-dense immunoreaction products indicating CB-LI were distributed diffusely in axoplasm of the axon terminals, no mitochondria, however, were not labeled. Neither cell bodies nor cytoplasmic extensions of the terminal Schwann cells exhibited CB-LI. CB was presumed to be involved in the maintenance of Ca2+ homeostasis in the mechano-electric transduction in mechanoreceptors in the periodontal ligament.[1]

References

  1. Immunohistochemical localization of calbindin D28k in the periodontal Ruffini endings of rat incisors. Ochi, K., Wakisaka, S., Youn, S.H., Hanada, K., Maeda, T. Neurosci. Lett. (1997) [Pubmed]
 
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