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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Parenteral acyclovir therapy for herpesvirus infections in man.

Acyclovir is a new antiviral agent which is highly active against herpesviruses in vitro and in laboratory animals. Twenty-three cancer patients with cutaneous and/or systemic herpes zoster or herpes simplex infections were treated with parenteral acyclovir. All had received previous specific treatment for their malignant disease and ten had undergone bone-marrow transplantation. The drug seemed to arrest the progress of the infections and was most effective when given early. Although two patients showed transient increases in blood-urea, possibly the result of acyclovir, the drug was remarkably non-toxic in the doses used.[1]

References

  1. Parenteral acyclovir therapy for herpesvirus infections in man. Selby, P.J., Powles, R.L., Janeson, B., Kay, H.E., Watson, J.G., Thornton, R., Morgenstern, G., Clink, H.M., McElwain, T.J., Prentice, H.G., Corringharn, R., Ross, M.G., Hoffbrand, A.V., Brigden, D. Lancet (1979) [Pubmed]
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