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MeSH Review

Herpesviridae Infections

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Disease relevance of Herpesviridae Infections


High impact information on Herpesviridae Infections


Chemical compound and disease context of Herpesviridae Infections


Biological context of Herpesviridae Infections


Anatomical context of Herpesviridae Infections


Gene context of Herpesviridae Infections

  • However to date the effects of acute herpesvirus infection on metabolism of APP in human neuronal-type cells have not been investigated [24].
  • Overall, the results suggest that the dipeptide prodrugs of ACV have a high affinity toward the intestinal oligopeptide transporter hPEPT1 and therefore seem to be promising candidates in the treatment of ocular and oral herpesvirus infections, because cornea and intestinal epithelia seem to express the oligopeptide transporters [25].
  • Herpesvirus infection of ICAM-1-deficient mice [26].
  • Although the precise details of IRF3 activation and interferon production in response to herpesvirus infection are still being elucidated, viral proteins that block components of the interferon pathway, particularly IRF3, have been identified and characterized [27].
  • Polymerase chain reaction as a diagnostic adjunct in herpesvirus infections of the nervous system [28].

Analytical, diagnostic and therapeutic context of Herpesviridae Infections


  1. Vidarabine therapy for severe herpesvirus infections. An unusual syndrome of chronic varicella and transient immunologic deficiency. Aronson, M.D., Phillips, C.F., Gump, D.W., Albertini, R.J., Phillips, C.A. JAMA (1976) [Pubmed]
  2. Interferon gamma regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels. Presti, R.M., Pollock, J.L., Dal Canto, A.J., O'Guin, A.K., Virgin, H.W. J. Exp. Med. (1998) [Pubmed]
  3. Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8. De Clercq, E., Naesens, L., De Bolle, L., Schols, D., Zhang, Y., Neyts, J. Rev. Med. Virol. (2001) [Pubmed]
  4. In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections. Rybak, R.J., Hartline, C.B., Qiu, Y.L., Zemlicka, J., Harden, E., Marshall, G., Sommadossi, J.P., Kern, E.R. Antimicrob. Agents Chemother. (2000) [Pubmed]
  5. Safety of famciclovir in patients with herpes zoster and genital herpes. Saltzman, R., Jurewicz, R., Boon, R. Antimicrob. Agents Chemother. (1994) [Pubmed]
  6. Visceral herpesvirus infections in leukemic patients receiving cytarabine. Buss, D.H., Scharyj, M., White, D.R. JAMA (1980) [Pubmed]
  7. Successful treatment of human genital herpes infections with 2-deoxy-D-glucose. Blough, H.A., Giuntoli, R.L. JAMA (1979) [Pubmed]
  8. Manganese superoxide dismutase as a target of autoantibodies in acute Epstein-Barr virus infection. Ritter, K., Kühl, R.J., Semrau, F., Eiffert, H., Kratzin, H.D., Thomssen, R. J. Exp. Med. (1994) [Pubmed]
  9. Genetic resistance factor for HIV-1 and immune response to varicella zoster virus. Wiencke, J.K., Kelsey, K.T., Zuo, Z.F., Weinberg, A., Wrensch, M.R. Lancet (2001) [Pubmed]
  10. Parenteral acyclovir therapy for herpesvirus infections in man. Selby, P.J., Powles, R.L., Janeson, B., Kay, H.E., Watson, J.G., Thornton, R., Morgenstern, G., Clink, H.M., McElwain, T.J., Prentice, H.G., Corringharn, R., Ross, M.G., Hoffbrand, A.V., Brigden, D. Lancet (1979) [Pubmed]
  11. Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy. Bacon, T.H., Levin, M.J., Leary, J.J., Sarisky, R.T., Sutton, D. Clin. Microbiol. Rev. (2003) [Pubmed]
  12. Impact of therapy With chlorambucil, fludarabine, or fludarabine plus chlorambucil on infections in patients with chronic lymphocytic leukemia: Intergroup Study Cancer and Leukemia Group B 9011. Morrison, V.A., Rai, K.R., Peterson, B.L., Kolitz, J.E., Elias, L., Appelbaum, F.R., Hines, J.D., Shepherd, L., Martell, R.E., Larson, R.A., Schiffer, C.A. J. Clin. Oncol. (2001) [Pubmed]
  13. Phase I evaluation of 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in immunosuppressed patients with herpesvirus infection. Young, C.W., Schneider, R., Leyland-Jones, B., Armstrong, D., Tan, C.T., Lopez, C., Watanabe, K.A., Fox, J.J., Philips, F.S. Cancer Res. (1983) [Pubmed]
  14. Genotypic characterization of the DNA polymerase and sensitivity to antiviral compounds of foscarnet-resistant herpes simplex virus type 1 (HSV-1) derived from a foscarnet-sensitive HSV-1 strain. Saijo, M., Suzutani, T., Morikawa, S., Kurane, I. Antimicrob. Agents Chemother. (2005) [Pubmed]
  15. Anti-complement immunofluorescence test for antibodies to human cytomegalovirus. Kettering, J.D., Schmidt, N.J., Gallo, D., Lennette, E.H. J. Clin. Microbiol. (1977) [Pubmed]
  16. Valacyclovir. Acosta, E.P., Fletcher, C.V. The Annals of pharmacotherapy. (1997) [Pubmed]
  17. Famciclovir for treatment of herpesvirus infections. Luber, A.D., Flaherty, J.F. The Annals of pharmacotherapy. (1996) [Pubmed]
  18. Caprine herpesvirus infection in Switzerland: some aspects of its pathogenicity. Waldvogel, A., Engels, M., Wild, P., Stünzi, H., Wyler, R. Zentralblatt Veterinarmedizin Reihe B (1981) [Pubmed]
  19. The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections. Heise, M.T., Virgin, H.W. J. Virol. (1995) [Pubmed]
  20. Central nervous system herpesvirus infection in systemic lupus erythematosus: diagnosis by endoretinal biopsy. Feinman, M.C., Friedberg, M.A., Schwartz, J.C., Pilkerton, A.R., Perman, K.I., Barth, W.F., Bunning, R.D. J. Rheumatol. (1993) [Pubmed]
  21. Multiple abortions associated with caprine herpesvirus infection in a goat herd. Williams, N.M., Vickers, M.L., Tramontin, R.R., Petrites-Murphy, M.B., Allen, G.P. J. Am. Vet. Med. Assoc. (1997) [Pubmed]
  22. Inclusion body disease of falcons (Herpesvirus infection) in an American kestrel. Kocan, A.A., Potgieter, L.N., Kocan, K.M. J. Wildl. Dis. (1977) [Pubmed]
  23. Effect of herpesvirus infections on T-lymphocyte subpopulations and blastogenic responses in renal transplant recipients receiving cyclosporine. Rinaldo, C.R., DeBiasio, R.L., Hamoudi, W.H., Rabin, B., Liebert, M., Hakala, T.R. Clin. Immunol. Immunopathol. (1986) [Pubmed]
  24. Herpes simplex virus interferes with amyloid precursor protein processing. Shipley, S.J., Parkin, E.T., Itzhaki, R.F., Dobson, C.B. BMC Microbiol. (2005) [Pubmed]
  25. Interactions of the dipeptide ester prodrugs of acyclovir with the intestinal oligopeptide transporter: competitive inhibition of glycylsarcosine transport in human intestinal cell line-Caco-2. Anand, B.S., Patel, J., Mitra, A.K. J. Pharmacol. Exp. Ther. (2003) [Pubmed]
  26. Herpesvirus infection of ICAM-1-deficient mice. Jung, H.W., Jung, C.R., Choi, B.K., Vinay, D.S., Hill, J.M., Gebhardt, B.M., Kwon, B.S. Curr. Eye Res. (2004) [Pubmed]
  27. Herpesviruses and the innate immune response. Mossman, K.L., Ashkar, A.A. Viral Immunol. (2005) [Pubmed]
  28. Polymerase chain reaction as a diagnostic adjunct in herpesvirus infections of the nervous system. Kleinschmidt-DeMasters, B.K., DeBiasi, R.L., Tyler, K.L. Brain Pathol. (2001) [Pubmed]
  29. Glucose analogues in the chemotherapy of herpesvirus infections. Blough, H.A., Ray, E.K. Pharmacol. Ther. (1980) [Pubmed]
  30. The immunosuppressive agent mycophenolate mofetil markedly potentiates the activity of lobucavir [1R(1alpha,2beta,3alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl]guanine against different herpes viruses. Neyts, J., De Clercq, E. Transplantation (1999) [Pubmed]
  31. Comparison of the efficacy of vidarabine, its carbocyclic analog (cyclaradine), and cyclaradine-5'-methoxyacetate in the treatment of herpes simplex virus type 1 encephalitis in mice. Shannon, W.M., Westbrook, L., Arnett, G., Daluge, S., Lee, H., Vince, R. Antimicrob. Agents Chemother. (1983) [Pubmed]
  32. Pneumonia caused by herpesviruses in recipients of hematopoietic cell transplants. Taplitz, R.A., Jordan, M.C. Seminars in respiratory infections. (2002) [Pubmed]
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