- Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation. Vrtala, S., Ball, T., Spitzauer, S., Pandjaitan, B., Suphioglu, C., Knox, B., Sperr, W.R., Valent, P., Kraft, D., Valenta, R. J. Immunol. (1998)