Gene Review:
COMP - cartilage oligomeric matrix protein
Homo sapiens
Synonyms:
Cartilage oligomeric matrix protein, EDM1, EPD1, MED, PSACH, ...
Michel,
Fajardo,
Kraus,
Mufson,
Saxne,
Canfield,
Strandberg,
Czerwenka,
Skogh,
van den Berg ,
Geisler,
Jaffar,
Frey-Rindova,
Roberts,
Siegel,
Prazak,
Farrington,
Vytásek,
Chilcote,
Frey,
Senolt,
Mary E. Herndon,
Gay,
Kjeldsberg,
Yu,
Kong,
Meadows,
Coenen-de Roo ,
Hayes,
Levey,
Leroy,
Heinegård,
Joosten,
Dziobon,
Mortier,
Xu,
Cole,
Krailo,
Tchetverikov,
Hecht,
Neidhart,
Steinherz,
Ilalov,
Weber,
Leirisalo-Repo,
Boot-Handford,
Jack Lawler,
Liu,
Chapman,
Gay,
Briggs,
Hecht,
Sposto,
Unger,
Zaucke,
Kullich,
Hummel,
Jüngel,
Söderlin,
Mur,
Gay,
Niksic,
Kadin,
Morse,
Kumar,
Jacqueline T. Hecht,
Neidhart,
Häuselmann,
Colombani,
Kastbom,
Bosserhoff,
Helsen,
Termuhlen,
Rocky S. Tuan,
Gay,
Heimburg,
von Knoch,
Nichlesh Patel,
Schünemann,
Faye Hui Chen,
Haynes,
Vobůrka,
Lubberts,
Heagerty,
Müller-Ladner,
Sehgal,
Kautiainen,
Pavelka,
Di Cesare,
Vilím,
Aglas,
- Human monoclonal rheumatoid synovial B lymphocyte hybridoma with a new disease-related specificity for cartilage oligomeric matrix protein. Souto-Carneiro, M.M., Burkhardt, H., Müller, E.C., Hermann, R., Otto, A., Kraetsch, H.G., Sack, U., König, A., Heinegård, D., Müller-Hermelink, H.K., Krenn, V. J. Immunol. (2001)
- Regulation of cartilage oligomeric matrix protein synthesis in human synovial cells and articular chondrocytes. Recklies, A.D., Baillargeon, L., White, C. Arthritis Rheum. (1998)
- The involvement of matrix glycoproteins in vascular calcification and fibrosis: an immunohistochemical study. Canfield, A.E., Farrington, C., Dziobon, M.D., Boot-Handford, R.P., Heagerty, A.M., Kumar, S.N., Roberts, I.S. J. Pathol. (2002)
- Clinical and radiographic features of multiple epiphyseal dysplasia not linked to the COMP or type IX collagen genes. Mortier, G.R., Chapman, K., Leroy, J.L., Briggs, M.D. Eur. J. Hum. Genet. (2001)
- Expression of mutant cartilage oligomeric matrix protein in human chondrocytes induces the pseudoachondroplasia phenotype. Merritt, T.M., Alcorn, J.L., Haynes, R., Hecht, J.T. J. Orthop. Res. (2006)
- Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels. Chen, H.C., Shah, S.H., Li, Y.J., Stabler, T.V., Jordan, J.M., Kraus, V.B. Arthritis Rheum. (2008)
- Sexually transmitted diseases in Swedish women with experience of casual sex with men of foreign nationalities within Sweden. Arvidson, M., Hellberg, D., Mårdh, P.A. Acta obstetricia et gynecologica Scandinavica. (1995)
- Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice. Gleason, S.D., Shannon, H.E. Psychopharmacology (Berl.) (1997)
- m2 muscarinic acetylcholine receptor-immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer's disease: relationship with cholinergic and galaninergic perikarya. Mufson, E.J., Jaffar, S., Levey, A.I. J. Comp. Neurol. (1998)
- The insect immune protein hemolin is expressed during oogenesis and embryogenesis. Bettencourt, R., Assefaw-Redda, Y., Faye, I. Mech. Dev. (2000)
- Dialectical behavior therapy for depressed older adults: a randomized pilot study. Lynch, T.R., Morse, J.Q., Mendelson, T., Robins, C.J. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. (2003)
- Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia. Hecht, J.T., Nelson, L.D., Crowder, E., Wang, Y., Elder, F.F., Harrison, W.R., Francomano, C.A., Prange, C.K., Lennon, G.G., Deere, M. Nat. Genet. (1995)
- Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene. Briggs, M.D., Hoffman, S.M., King, L.M., Olsen, A.S., Mohrenweiser, H., Leroy, J.G., Mortier, G.R., Rimoin, D.L., Lachman, R.S., Gaines, E.S. Nat. Genet. (1995)
- The crystal structure of a five-stranded coiled coil in COMP: a prototype ion channel? Malashkevich, V.N., Kammerer, R.A., Efimov, V.P., Schulthess, T., Engel, J. Science (1996)
- Sensitivity to sunburn is associated with susceptibility to ultraviolet radiation-induced suppression of cutaneous cell-mediated immunity. Kelly, D.A., Young, A.R., McGregor, J.M., Seed, P.T., Potten, C.S., Walker, S.L. J. Exp. Med. (2000)
- Increased pentosidine, an advanced glycation end product, in serum and synovial fluid from patients with knee osteoarthritis and its relation with cartilage oligomeric matrix protein. Senolt, L., Braun, M., Olejárová, M., Forejtová, S., Gatterová, J., Pavelka, K. Ann. Rheum. Dis. (2005)
- The treatment of localized non-Hodgkin's lymphoma in children: a report from the Children's Cancer Study Group. Jenkin, R.D., Anderson, J.R., Chilcote, R.R., Coccia, P.F., Exelby, P.R., Kersey, J.H., Kushner, J.H., Meadows, A.T., Siegel, S.E., Sposto, R. J. Clin. Oncol. (1984)
- Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group. Sposto, R., Meadows, A.T., Chilcote, R.R., Steinherz, P.G., Kjeldsberg, C., Kadin, M.E., Krailo, M.D., Termuhlen, A.M., Morse, M., Siegel, S.E. Med. Pediatr. Oncol. (2001)
- CCNU, vincristine, methotrexate, and procarbazine treatment of relapsed small cell lung carcinoma. Poplin, E.A., Aisner, J., Van Echo, D.A., Whitacre, M., Wiernik, P.H. Cancer treatment reports. (1982)
- COMP mutations, chondrocyte function and cartilage matrix. Hecht, J.T., Hayes, E., Haynes, R., Cole, W.G. Matrix Biol. (2005)
- Analysis of the promoter region of human cartilage oligomeric matrix protein (COMP). Deere, M., Rhoades Hall, C., Gunning, K.B., LeFebvre, V., Ridall, A.L., Hecht, J.T. Matrix Biol. (2001)
- Pseudoachondroplasia and multiple epiphyseal dysplasia: New etiologic developments. Unger, S., Hecht, J.T. Am. J. Med. Genet. (2001)
- Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. Månsson, B., Carey, D., Alini, M., Ionescu, M., Rosenberg, L.C., Poole, A.R., Heinegård, D., Saxne, T. J. Clin. Invest. (1995)
- Unique matrix structure in the rough endoplasmic reticulum cisternae of pseudoachondroplasia chondrocytes. Merritt, T.M., Bick, R., Poindexter, B.J., Alcorn, J.L., Hecht, J.T. Am. J. Pathol. (2007)
- Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts. Dodge, G.R., Hawkins, D., Boesler, E., Sakai, L., Jimenez, S.A. Osteoarthr. Cartil. (1998)
- Inhibitory effects of leflunomide therapy on the activity of matrixmetalloproteinase-9 and the release of cartilage oligomeric matrix protein in patients with rheumatoid arthritis. Kullich, W.C., Mur, E., Aglas, F., Niksic, F., Czerwenka, C. Clin. Exp. Rheumatol. (2006)
- Expression of extracellular matrix molecules typical of articular cartilage in the human scapholunate interosseous ligament. Milz, S., Aktas, T., Putz, R., Benjamin, M. J. Anat. (2006)
- Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis. Joosten, L.A., Lubberts, E., Helsen, M.M., Saxne, T., Coenen-de Roo , C.J., Heinegård, D., van den Berg , W.B. Arthritis Res. (1999)
- Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins. Gagarina, V., Carlberg, A.L., Pereira-Mouries, L., Hall, D.J. J. Biol. Chem. (2008)
- ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein. Liu, C.J., Kong, W., Ilalov, K., Yu, S., Xu, K., Prazak, L., Fajardo, M., Sehgal, B., Di Cesare, P.E. FASEB J. (2006)
- Selective intracellular retention of extracellular matrix proteins and chaperones associated with pseudoachondroplasia. Vranka, J., Mokashi, A., Keene, D.R., Tufa, S., Corson, G., Sussman, M., Horton, W.A., Maddox, K., Sakai, L., Bächinger, H.P. Matrix Biol. (2001)
- FTIR-Spectroscopy of multistranded coiled coil proteins. Heimburg, T., Schünemann, J., Weber, K., Geisler, N. Biochemistry (1999)
- Role of TSP-5/COMP in pseudoachondroplasia. Posey, K.L., Hayes, E., Haynes, R., Hecht, J.T. Int. J. Biochem. Cell Biol. (2004)
- Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein. Neidhart, M., Zaucke, F., von Knoch, R., Jüngel, A., Michel, B.A., Gay, R.E., Gay, S. Ann. Rheum. Dis. (2005)
- Cartilage oligomeric matrix protein expression in hepatocellular carcinoma and the cirrhotic liver. Xiao, Y., Kleeff, J., Guo, J., Gazdhar, A., Liao, Q., Di Cesare, P.E., Büchler, M.W., Friess, H. J. Gastroenterol. Hepatol. (2004)
- COL9A3: A third locus for multiple epiphyseal dysplasia. Paassilta, P., Lohiniva, J., Annunen, S., Bonaventure, J., Le Merrer, M., Pai, L., Ala-Kokko, L. Am. J. Hum. Genet. (1999)
- A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity. Czarny-Ratajczak, M., Lohiniva, J., Rogala, P., Kozlowski, K., Perälä, M., Carter, L., Spector, T.D., Kolodziej, L., Seppänen, U., Glazar, R., Królewski, J., Latos-Bielenska, A., Ala-Kokko, L. Am. J. Hum. Genet. (2001)
- Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners. Neidhart, M., Müller-Ladner, U., Frey, W., Bosserhoff, A.K., Colombani, P.C., Frey-Rindova, P., Hummel, K.M., Gay, R.E., Häuselmann, H., Gay, S. Osteoarthr. Cartil. (2000)
- Double heterozygosity for pseudoachondroplasia and spondyloepiphyseal dysplasia congenita. Unger, S., Korkko, J., Krakow, D., Lachman, R.S., Rimoin, D.L., Cohn, D.H. Am. J. Med. Genet. (2001)
- Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan. Chen, F.H., Herndon, M.E., Patel, N., Hecht, J.T., Tuan, R.S., Lawler, J. J. Biol. Chem. (2007)
- Monoclonal antibodies to human cartilage oligomeric matrix protein: epitope mapping and characterization of sandwich ELISA. Vilím, V., Vobůrka, Z., Vytásek, R., Senolt, L., Tchetverikov, I., Kraus, V.B., Pavelka, K. Clin. Chim. Acta (2003)
- Antibodies against cyclic citrullinated peptide (CCP) and levels of cartilage oligomeric matrix protein (COMP) in very early arthritis: relation to diagnosis and disease activity. Söderlin, M.K., Kastbom, A., Kautiainen, H., Leirisalo-Repo, M., Strandberg, G., Skogh, T. Scand. J. Rheumatol. (2004)