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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 64 documents. Results 1 - 10.

Homo sapiens
Gene: ... in rat CYP11B2 and all known CYP11B genes of other animals, was modified in rat CYP11B1 and- B3 genes.... Analytical, diagnostic and therapeutic context of CYP11B2 In all patients we amplified the CYP11B1 gene...Disease relevance of CYP11B2 Mutations in CYP11B2 result in aldosterone synthase( corticosterone...
Mus musculus
Gene: ... Disease relevance of Cyp11b2 Physical mapping of overlapping cosmid and phage isolates defined two genes( designated Cyp11b- 1 and Cyp11b- 2 in the standard nomenclature for cytochrome P450 genes..., and aldosterone synthase. Psychiatry related information on Cyp11b2 In a time study experiment we found that P450C... / Synonyms: Cyp11b-2
Rattus norvegicus
Gene: ... High impact information on Cyp11b2 CMA enhanced serum aldosterone levels by 54% and increased the expression of aldosterone synthase in the adrenal gland by 134% after 5d of CMA. In situ hybridization studies revealed that cytochrome P- 450 ALDO synthetase mRNA was confined to the subcapsular zona... / Synonyms: Cyp11b-2
Bos taurus
Gene: ... High impact information on CYP11B2 Changed ratios of glucocorticoids/ mineralocorticoids caused by point mutations in the putative I- helix regions of CYP11B1 and CYP11B2....
MeSH term: ... conversion in the coding region of CYP11B1 or in the promoter of CYP11B2) that could explain a positive... and gene conversion of immunoglobulin variable regions. This mutation is not normally present in CYP11B2...Disease relevance of Gene Conversion All these mutations result in a hyper- recombination phenotype...
Chemical compound: ... : evidence for common signaling mechanisms. CYP11B2 mRNA levels were increased in cultured zona glomerulosa...
Chemical compound: ... Disease relevance of CORTICOSTERONE Mutations in CYP11B2 result in aldosterone synthase...) and corticosterone is reduced. Despite normal survival in utero, all Ftz- F1 null animals died by postnatal day 8... up- regulation of TNF- alpha, improved TNBS colitis, and enhanced plasma corticosterone. In all...
MeSH term: ... of the adrenal cortex termed CYP11B2. Delivery of cholesterol to inner mitochondrial membranes is rate- limiting... failure in the synthesis of all classes of steroid hormones and by an immune response against the steroid... of androgen remain unclear. At the onset, all patients with autoimmune AD( 100 %) had detectable adrenal...
MeSH term: ... was correlated with the GFR levels. The associations AGT TT- AT1R AC and CYP11B2 CC- ACE DD showed a possible... with various underlying renal diseases. Toxic reactions to all regimens included vomiting, which was least...
MeSH term: ... . Genetic variation in the gene encoding aldosterone synthase( CYP11B2) has previously been shown... ventricles, those from all patients with left ventricular hypertrophy had lower creatine kinase activity... Disruption of the leptin signaling pathway within the heart causes left ventricular hypertrophy( LVH). All 5...

 

 
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