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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 76 documents. Results 1 - 10.

Homo sapiens
Gene: ... of Tregs, were determined for all subjects. Physical interactions of FOXP3 Using chromatin...Disease relevance of FOXP3 Reduced frequency of FOXP3+ CD4+ CD25+ regulatory T cells in patients with chronic graft- versus- host disease. Decreased FOXP3 levels in multiple sclerosis patients. FOXP3...
Mus musculus
Gene: ... of peripheral Foxp3- expressing regulatory T cells, and survival of CD4 (+) T cells all depended on TGF- beta...Disease relevance of Foxp3 PSI- APC Treg cells expressed high levels of Foxp3, inhibited... to bacterial- associated Ag. Homeostatic maintenance of natural Foxp3 (+) CD25 (+) CD4 (+) regulatory T cells...
Macaca mulatta
Gene: ... High impact information on FOXP3 Sorted cells with the surface phenotype CD4 (+) CD25 (+) CD127( low) had higher levels of intracellular FOXP3 and CTLA- 4 and, as determined by functional assays, were suppressive, hypoproliferative, and poorly responsive to TCR signaling....
Bos taurus
Gene: ... High impact information on FOXP3 The expression of Foxp3 mRNA also increased and was accompanied by the upregulation of CD152 and the downregulation of IL- 2 transcription, suggesting that cells in this subpopulation are T( regs)....
MeSH term: ... - Lymphocytes, Regulatory Lack of Foxp3 leads to development of fatal autoimmune lymphoproliferative disease; furthermore, ectopic Foxp3 expression can phenotypically convert effector T cells to regulatory T cells...- deficient mice. Implications for the nonredundant function of IL- 2. Upregulation of TGF- beta, FOXP3...
MeSH term: ... by day 7, hearts from IP- 10 (-/-) mice survived long term. Recruitment of Foxp3+ T regulatory cells... were markedly decreased. Real- time polymerase chain reaction showed that intragraft Foxp3 levels...
MeSH term: ... ) cells) expressing the forkhead family transcription factor Foxp3 are critical mediators of dominant... tolerance is mediated via the Fas/ Fas- ligand system. FOXP3 is playing an essential role for T regulatory.... Insulin was detected in all thymus tissues examined and class III VNTR alleles were associated with 2...
MeSH term: ... demonstrated that non- Foxp3- expressing CD4 T cells could not be converted into Foxp3- expressing cells upon...
MeSH term: ... in chronic adult periodontitis. FOXP3, a characteristic marker for CD4+ CD25+ Tr cells, TGF- beta1 and IL- 10...
Homo sapiens
Gene: ... context of TGFB1 The frequency of CD25+ memory CD4+ T cells and transient FOXP3 mRNA expression by CD4... production, and eosinophilia. These cells recognize antigen as do all T cells, but they secrete... cells, all of the Ski protein was found in Smad3- containing complexes that accumulated in the nucleus...

 

 
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