Your search matched a total of 159 documents. Results 1 - 10.
Mus musculus
Gene: ... Disease relevance of Nf2 Recent studies suggest that Nf2 loss also contributes to tumor metastasis. Biallelic mutations in the neurofibromatosis 2( NF2) gene are linked to schwannoma and meningioma tumorigenesis. Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human... / Synonyms: Nf-2
Danio rerio
Gene: ... Disease relevance of nf2 A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie... gene nf2, develops extrahepatic choledochal cysts in the common bile duct, suggesting that this gene regulates division of biliary cells during development and that nf2 may play a role in the hyperplastic... / Synonyms: NF2a; nf2
Homo sapiens
Gene: ... including multiple meningiomas. The NF2 protein, called schwannomin or merlin, is absent in virtually all...Disease relevance of NF2 We have identified a candidate gene for the NF2 tumor suppressor that has suffered nonoverlapping deletions in DNA from two independent NF2 families and alterations in meningiomas...
MeSH term: ... Disease relevance of Genes, Neurofibromatosis 2 Mutations in the neurofibromatosis type 2( NF2.... In this study, we have evaluated neurofibromatosis type 2( NF2) gene alterations in eight PNTs using archival formaldehyde- fixed, paraffin- embedded tissue. Biallelic mutations in the neurofibromatosis 2( NF2) gene... / Synonyms: Gene, nf 2; Gene, nf2; Genes, nf 2
MeSH term: ... neurofibromatosis with bilateral vestibular schwannomas were analyzed for mutations in the NF2 gene. Neurofibromatosis 2( NF2 ), also known as bilateral acoustic neurofibromatosis or central neurofibromatosis... malignant progression in human gliomas. A diagnosis of Neurofibromatosis- 2( NF2) is strongly suspected... / Synonyms: Central NF2 Neurofibromatoses; Central NF2 Neurofibromatosis; NF2 (Neurofibromatosis 2)
Rattus norvegicus
Gene: ... Disease relevance of Nf2 These findings contrast with data reported previously for human mesotheliomas, in which the NF2 gene was found to be mutated in 40% of cases. Individuals affected with NF2...- encoding merlin/ schwannomin. High impact information on Nf2 Neurofibromatosis 2( NF2) tumor suppressor...
MeSH term: ... the cerebellum and other areas of the central nervous system. Neurofibromatosis 2( NF2) is a dominantly inherited.... All four glycine transporters of the" GLYT family" also belong to the neurotransmitter superfamily... in the embryonic central nervous system and on all sensory axon pathways in the peripheral nervous system. Neurons...
MeSH term: ... Disease relevance of Meningioma The NF2 protein, called schwannomin or merlin, is absent... on Meningioma The involvement of calpain- dependent proteolysis of the tumor suppressor NF2( merlin) in schwannomas and meningiomas. Biallelic NF2 gene inactivation is common in sporadic and in neurofibromatosis...
MeSH term: ... whether this mechanism may also apply for the neurofibromatosis type- 2 gene( NF2) which, when mutated... ." To compare the molecular- genetic basis of schwannomatosis with NF2, we examined the NF2 locus in 20... phosphorylation in the rat schwannoma cell line RT4. Exon scanning for mutation of the NF2 gene in schwannomas...
MeSH term: ... , grade III tumors, and distal metastasis. These data strongly support the notion that NF2 is the sole... alteration of NF2, following the classic" two hit" theory. TP53 status[ mutations, immunostaining, and loss...53 and CDKN2A mutations, CDKN2A CpG- island methylation and ploidy during neoplastic progression. All...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
