Your search matched a total of 47 documents. Results 1 - 10.
Homo sapiens
Gene: ... Phox2b is essential for the development of autonomic neural crest derivatives. Here we show that all...Disease relevance of PHOX2B Finally, PHOX2B proteins carrying mutations responsible for CCHS... suggested that PHOX2B is able to bind the cell- specific element in the 5' regulatory region of the TLX2... / Synonyms: PHOX2B homeodomain protein; Phox2b
Mus musculus
Gene: ... make Phox2b a master regulator of all central and peripheral noradrenergic differentiation. Here, we...Disease relevance of Phox2b Constriction of the pupil is a parasympathetic response mediated by the ciliary ganglion and we find that in Phox2b heterozygous mutants it is highly atrophic. Haploinsufficiency... / Synonyms: PHOX2B homeodomain protein
Gallus gallus
Gene: ... Disease relevance of PHOX2B The expression of Mash1( Cash1 ), Phox2b and Phox2a in the chick... marker genes. High impact information on PHOX2B We further show that both the PH and P/ M sites are essential for Hox- Pbx- Prep ternary complex formation and regulation of the Phox2b enhancer activity...
Rattus norvegicus
Gene: ... High impact information on Phox2b_ predicted We have studied the expression of the homeodomain transcriptional neuronal regulators Phox2a, Phox2b and the non- neuronal Schwann cell response using the marker S... retinoic acid( RA) treatment of pregnant dams. Anatomical context of Phox2b_ predicted These results...
MeSH term: ... . The paralogous paired- like homeobox genes Phox2a and Phox2b are involved in the development of specific neural... in the peripheral nervous system and that some but not all of these receptors are CCKA receptors. Our results...
MeSH term: ... or antigen and are unable to derepress the synthesis of the enzyme. Distinct pathogenetic mechanisms for PHOX2B associated polyalanine expansions and frameshift mutations in congenital central hypoventilation... inhibitors. Here we report that although all nonsense and frameshift mutations that cause premature...
MeSH term: ... autonomic nervous system development, we have tested the transcriptional activity of WT and mutant PHOX2B.../ or autonomic nervous system discharge. Gene context of Autonomic Nervous System Phox2b is necessary... amyloid polyneuropathy but is unique in that the age of onset is in the seventh decade in all family...
MeSH term: ... shown that heterozygous mutations of PHOX2B may account for several combined or isolated disorders... that hydralazine does not produce uniform vasodilation in all organs and that the cardiovascular actions...
MeSH term: ... ). Haploinsufficiency for Phox2b in mice causes dilated pupils and atrophy of the ciliary ganglion: mechanistic insights into human congenital central hypoventilation syndrome. We also show that Phox2b heterozygous mutants have... syndrome, which is associated with heterozygous mutations in PHOX2B. It appears that small to moderate...
MeSH term: ... Syndromes CONCLUSION: Although their respiratory phenotype was much less severe than CCHS, the Phox2b... of the transcription factor Phox2b would display sleep- disordered breathing. Clinical conditions altering IL- 1 or TNF... basis for sleep- disordered breathing after nicotine exposure. RESULTS: All 10 patients had sleep apnea...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
