Gene Review:
Phox2b - paired-like homeobox 2b
Mus musculus
Synonyms:
Dilp1, GENA 269, NBPhox, Neuroblastoma Phox, PHOX2B homeodomain protein, ...
- Haploinsufficiency for Phox2b in mice causes dilated pupils and atrophy of the ciliary ganglion: mechanistic insights into human congenital central hypoventilation syndrome. Cross, S.H., Morgan, J.E., Pattyn, A., West, K., McKie, L., Hart, A., Thaung, C., Brunet, J.F., Jackson, I.J. Hum. Mol. Genet. (2004)
- Sleep-disordered breathing in newborn mice heterozygous for the transcription factor Phox2b. Durand, E., Dauger, S., Pattyn, A., Gaultier, C., Goridis, C., Gallego, J. Am. J. Respir. Crit. Care Med. (2005)
- Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors. Pattyn, A., Vallstedt, A., Dias, J.M., Samad, O.A., Krumlauf, R., Rijli, F.M., Brunet, J.F., Ericson, J. Genes Dev. (2003)
- Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3. Qian, Y., Fritzsch, B., Shirasawa, S., Chen, C.L., Choi, Y., Ma, Q. Genes Dev. (2001)
- Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. Coppola, E., Pattyn, A., Guthrie, S.C., Goridis, C., Studer, M. EMBO J. (2005)
- Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Pattyn, A., Goridis, C., Brunet, J.F. Mol. Cell. Neurosci. (2000)
- The Phox2b transcription factor coordinately regulates neuronal cell cycle exit and identity. Dubreuil, V., Hirsch, M.R., Pattyn, A., Brunet, J.F., Goridis, C. Development (2000)
- Sp proteins and Phox2b regulate the expression of the human Phox2a gene. Flora, A., Lucchetti, H., Benfante, R., Goridis, C., Clementi, F., Fornasari, D. J. Neurosci. (2001)
- Role of Phox2b and Mash1 in the generation of the vestibular efferent nucleus. Tiveron, M.C., Pattyn, A., Hirsch, M.R., Brunet, J.F. Dev. Biol. (2003)
- A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture. Young, H.M., Hearn, C.J., Ciampoli, D., Southwell, B.R., Brunet, J.F., Newgreen, D.F. Dev. Biol. (1998)
- Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut. Young, H.M., Ciampoli, D., Hsuan, J., Canty, A.J. Dev. Dyn. (1999)
- Ventilatory response to hyperoxia in newborn mice heterozygous for the transcription factor Phox2b. Ramanantsoa, N., Vaubourg, V., Dauger, S., Matrot, B., Vardon, G., Chettouh, Z., Gaultier, C., Goridis, C., Gallego, J. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2006)
- Development of chromaffin cells depends on MASH1 function. Huber, K., Brühl, B., Guillemot, F., Olson, E.N., Ernsberger, U., Unsicker, K. Development (2002)
- Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. Young, H.M., Bergner, A.J., Müller, T. J. Comp. Neurol. (2003)